Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke

Risk of infection is high after stroke, but the causes are not clear. Here the authors implicate altered beta–adrenergic signalling after stroke that results in a reduction in IgM-mediated protection by marginal zone B cells.

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Detalles Bibliográficos
Autores principales: Laura McCulloch, Craig J. Smith, Barry W. McColl
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/cffdc7d0c392482bac92e1563bf561d3
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Descripción
Sumario:Risk of infection is high after stroke, but the causes are not clear. Here the authors implicate altered beta–adrenergic signalling after stroke that results in a reduction in IgM-mediated protection by marginal zone B cells.