Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke
Risk of infection is high after stroke, but the causes are not clear. Here the authors implicate altered beta–adrenergic signalling after stroke that results in a reduction in IgM-mediated protection by marginal zone B cells.
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Nature Portfolio
2017
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oai:doaj.org-article:cffdc7d0c392482bac92e1563bf561d32021-12-02T15:38:42ZAdrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke10.1038/ncomms150512041-1723https://doaj.org/article/cffdc7d0c392482bac92e1563bf561d32017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms15051https://doaj.org/toc/2041-1723Risk of infection is high after stroke, but the causes are not clear. Here the authors implicate altered beta–adrenergic signalling after stroke that results in a reduction in IgM-mediated protection by marginal zone B cells.Laura McCullochCraig J. SmithBarry W. McCollNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017) |
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Science Q Laura McCulloch Craig J. Smith Barry W. McColl Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke |
description |
Risk of infection is high after stroke, but the causes are not clear. Here the authors implicate altered beta–adrenergic signalling after stroke that results in a reduction in IgM-mediated protection by marginal zone B cells. |
format |
article |
author |
Laura McCulloch Craig J. Smith Barry W. McColl |
author_facet |
Laura McCulloch Craig J. Smith Barry W. McColl |
author_sort |
Laura McCulloch |
title |
Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke |
title_short |
Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke |
title_full |
Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke |
title_fullStr |
Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke |
title_full_unstemmed |
Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke |
title_sort |
adrenergic-mediated loss of splenic marginal zone b cells contributes to infection susceptibility after stroke |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/cffdc7d0c392482bac92e1563bf561d3 |
work_keys_str_mv |
AT lauramcculloch adrenergicmediatedlossofsplenicmarginalzonebcellscontributestoinfectionsusceptibilityafterstroke AT craigjsmith adrenergicmediatedlossofsplenicmarginalzonebcellscontributestoinfectionsusceptibilityafterstroke AT barrywmccoll adrenergicmediatedlossofsplenicmarginalzonebcellscontributestoinfectionsusceptibilityafterstroke |
_version_ |
1718386142433247232 |