Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke

Risk of infection is high after stroke, but the causes are not clear. Here the authors implicate altered beta–adrenergic signalling after stroke that results in a reduction in IgM-mediated protection by marginal zone B cells.

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Autores principales: Laura McCulloch, Craig J. Smith, Barry W. McColl
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/cffdc7d0c392482bac92e1563bf561d3
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spelling oai:doaj.org-article:cffdc7d0c392482bac92e1563bf561d32021-12-02T15:38:42ZAdrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke10.1038/ncomms150512041-1723https://doaj.org/article/cffdc7d0c392482bac92e1563bf561d32017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms15051https://doaj.org/toc/2041-1723Risk of infection is high after stroke, but the causes are not clear. Here the authors implicate altered beta–adrenergic signalling after stroke that results in a reduction in IgM-mediated protection by marginal zone B cells.Laura McCullochCraig J. SmithBarry W. McCollNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Laura McCulloch
Craig J. Smith
Barry W. McColl
Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke
description Risk of infection is high after stroke, but the causes are not clear. Here the authors implicate altered beta–adrenergic signalling after stroke that results in a reduction in IgM-mediated protection by marginal zone B cells.
format article
author Laura McCulloch
Craig J. Smith
Barry W. McColl
author_facet Laura McCulloch
Craig J. Smith
Barry W. McColl
author_sort Laura McCulloch
title Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke
title_short Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke
title_full Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke
title_fullStr Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke
title_full_unstemmed Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke
title_sort adrenergic-mediated loss of splenic marginal zone b cells contributes to infection susceptibility after stroke
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/cffdc7d0c392482bac92e1563bf561d3
work_keys_str_mv AT lauramcculloch adrenergicmediatedlossofsplenicmarginalzonebcellscontributestoinfectionsusceptibilityafterstroke
AT craigjsmith adrenergicmediatedlossofsplenicmarginalzonebcellscontributestoinfectionsusceptibilityafterstroke
AT barrywmccoll adrenergicmediatedlossofsplenicmarginalzonebcellscontributestoinfectionsusceptibilityafterstroke
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