IL-10 suppression of NK/DC crosstalk leads to poor priming of MCMV-specific CD4 T cells and prolonged MCMV persistence.

IL-10 suppression of NK/DC crosstalk leads to poor priming of MCMV-specific CD4 T cells and prolonged MCMV persistence.

IL-10 is an anti-inflammatory cytokine that regulates the extent of host immunity to infection by exerting suppressive effects on different cell types. Herpes viruses induce IL-10 to modulate the virus-host balance towards their own benefit, resulting in prolonged virus persistence. To define the ce...

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Detalles Bibliográficos
Autores principales: Sanja Mandaric, Senta M Walton, Thomas Rülicke, Kirsten Richter, Mathilde J H Girard-Madoux, Björn E Clausen, Antonija Zurunic, Masahito Kamanaka, Richard A Flavell, Stipan Jonjic, Annette Oxenius
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/d001c32405c14df9b7e5cd2659e58db8
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