c-Jun amino-terminal kinase-1 mediates glucose-responsive upregulation of the RNA editing enzyme ADAR2 in pancreatic beta-cells.

A-to-I RNA editing catalyzed by the two main members of the adenosine deaminase acting on RNA (ADAR) family, ADAR1 and ADAR2, represents a RNA-based recoding mechanism implicated in a variety of cellular processes. Previously we have demonstrated that the expression of ADAR2 in pancreatic islet β-ce...

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Autores principales: Liu Yang, Ping Huang, Feng Li, Liyun Zhao, Yongliang Zhang, Shoufeng Li, Zhenji Gan, Anning Lin, Wenjun Li, Yong Liu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/d0089e104c204b3b90f1c92cf0d8c1d5
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