Blood level of anti-HBS in health care staff of Amirkola Hospital, 2001

Background and Objective: About 3-5% of Iranian general population are carriers of hepatitis B virus and about 15% of infected persons will be prone to chronic hepatitis and get cirrhosis and primary liver carcinoma. Up to now no therapeutic regimen has been introduced to eradicate completely this i...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: R Savad Koohi, MA Hosseinian
Formato: article
Lenguaje:EN
FA
Publicado: Babol University of Medical Sciences 2003
Materias:
R
Acceso en línea:https://doaj.org/article/d00efdf8d3c54f36985ca3f7fec0bbdc
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:d00efdf8d3c54f36985ca3f7fec0bbdc
record_format dspace
spelling oai:doaj.org-article:d00efdf8d3c54f36985ca3f7fec0bbdc2021-11-10T09:18:07ZBlood level of anti-HBS in health care staff of Amirkola Hospital, 20011561-41072251-7170https://doaj.org/article/d00efdf8d3c54f36985ca3f7fec0bbdc2003-04-01T00:00:00Zhttp://jbums.org/article-1-2772-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: About 3-5% of Iranian general population are carriers of hepatitis B virus and about 15% of infected persons will be prone to chronic hepatitis and get cirrhosis and primary liver carcinoma. Up to now no therapeutic regimen has been introduced to eradicate completely this information. The objective of this study was to evaluate immunity status of health care staff of Amirkola children hospital. Methods: This cross-sectional study was performed on 153 health care personnel of Amirkola children hospital (Babol). At first, a questionnaire included information about the time and number of vaccination was completed. Anti-HBC, Anti-HBS and HBsAg were examined by Radim (ELISA method). Findings: From 150 subjects, 132 (88%) of them were vaccinated against hepatitis B and 18 (12%) had no positive history of vaccination. Also, 6 cases were excluded due to their Anti-HBC positive results. The mean age of studied cases was 28.5±8.3 years. On average, 3.8±2 dosage of vaccine was received by subjects. The time interval after the last vaccination was 3.9±1.98 years. With consideration of Anti-HBS=10 mIu/ml as a cut-off value, 68.6% of subjects were immunized against hepatitis B and the mean titer of Anti-HBS was 263.9±391.3 mIu/ml. Conclusion: According to the results and decreased of immunity in 31.4% of health care personnel who were vaccinated against hepatitis B, it is suggested Anti-HBS titer should be examined 2-3 months after vaccination and Anti-HBS titer in immunized patients be controlled every 5-7 years and then booster vaccine be injected after reducing Anti-HBS titer to below protective level.R Savad KoohiMA HosseinianBabol University of Medical Sciencesarticlehepatitis bvaccinationanti-hbshealth care staffMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 5, Iss 2, Pp 38-42 (2003)
institution DOAJ
collection DOAJ
language EN
FA
topic hepatitis b
vaccination
anti-hbs
health care staff
Medicine
R
Medicine (General)
R5-920
spellingShingle hepatitis b
vaccination
anti-hbs
health care staff
Medicine
R
Medicine (General)
R5-920
R Savad Koohi
MA Hosseinian
Blood level of anti-HBS in health care staff of Amirkola Hospital, 2001
description Background and Objective: About 3-5% of Iranian general population are carriers of hepatitis B virus and about 15% of infected persons will be prone to chronic hepatitis and get cirrhosis and primary liver carcinoma. Up to now no therapeutic regimen has been introduced to eradicate completely this information. The objective of this study was to evaluate immunity status of health care staff of Amirkola children hospital. Methods: This cross-sectional study was performed on 153 health care personnel of Amirkola children hospital (Babol). At first, a questionnaire included information about the time and number of vaccination was completed. Anti-HBC, Anti-HBS and HBsAg were examined by Radim (ELISA method). Findings: From 150 subjects, 132 (88%) of them were vaccinated against hepatitis B and 18 (12%) had no positive history of vaccination. Also, 6 cases were excluded due to their Anti-HBC positive results. The mean age of studied cases was 28.5±8.3 years. On average, 3.8±2 dosage of vaccine was received by subjects. The time interval after the last vaccination was 3.9±1.98 years. With consideration of Anti-HBS=10 mIu/ml as a cut-off value, 68.6% of subjects were immunized against hepatitis B and the mean titer of Anti-HBS was 263.9±391.3 mIu/ml. Conclusion: According to the results and decreased of immunity in 31.4% of health care personnel who were vaccinated against hepatitis B, it is suggested Anti-HBS titer should be examined 2-3 months after vaccination and Anti-HBS titer in immunized patients be controlled every 5-7 years and then booster vaccine be injected after reducing Anti-HBS titer to below protective level.
format article
author R Savad Koohi
MA Hosseinian
author_facet R Savad Koohi
MA Hosseinian
author_sort R Savad Koohi
title Blood level of anti-HBS in health care staff of Amirkola Hospital, 2001
title_short Blood level of anti-HBS in health care staff of Amirkola Hospital, 2001
title_full Blood level of anti-HBS in health care staff of Amirkola Hospital, 2001
title_fullStr Blood level of anti-HBS in health care staff of Amirkola Hospital, 2001
title_full_unstemmed Blood level of anti-HBS in health care staff of Amirkola Hospital, 2001
title_sort blood level of anti-hbs in health care staff of amirkola hospital, 2001
publisher Babol University of Medical Sciences
publishDate 2003
url https://doaj.org/article/d00efdf8d3c54f36985ca3f7fec0bbdc
work_keys_str_mv AT rsavadkoohi bloodlevelofantihbsinhealthcarestaffofamirkolahospital2001
AT mahosseinian bloodlevelofantihbsinhealthcarestaffofamirkolahospital2001
_version_ 1718440234937483264