The predatory soil bacterium Lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-GMP-independent manner

The predatory soil bacterium Lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-GMP-independent manner

Li et al shows that the quorum sensing system component protein RpfG from Lysobacter, in addition to being a cyclic dimeric GMP (c-di-GMP) phosphodiesterase, also regulates the biosynthesis of an antifungal factor. They show that RpfG regulates the production of HSAF through a direct interaction wit...

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Autores principales: Kaihuai Li, Gaoge Xu, Bo Wang, Guichun Wu, Rongxian Hou, Fengquan Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/d0162b4a46e54e06ac7c7180f74386da
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spelling oai:doaj.org-article:d0162b4a46e54e06ac7c7180f74386da2021-12-02T17:26:48ZThe predatory soil bacterium Lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-GMP-independent manner10.1038/s42003-021-02660-72399-3642https://doaj.org/article/d0162b4a46e54e06ac7c7180f74386da2021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02660-7https://doaj.org/toc/2399-3642Li et al shows that the quorum sensing system component protein RpfG from Lysobacter, in addition to being a cyclic dimeric GMP (c-di-GMP) phosphodiesterase, also regulates the biosynthesis of an antifungal factor. They show that RpfG regulates the production of HSAF through a direct interaction with three hybrid two component system (HyTCS) proteins, providing insights into the antifungal defence in soil bacteria.Kaihuai LiGaoge XuBo WangGuichun WuRongxian HouFengquan LiuNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Kaihuai Li
Gaoge Xu
Bo Wang
Guichun Wu
Rongxian Hou
Fengquan Liu
The predatory soil bacterium Lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-GMP-independent manner
description Li et al shows that the quorum sensing system component protein RpfG from Lysobacter, in addition to being a cyclic dimeric GMP (c-di-GMP) phosphodiesterase, also regulates the biosynthesis of an antifungal factor. They show that RpfG regulates the production of HSAF through a direct interaction with three hybrid two component system (HyTCS) proteins, providing insights into the antifungal defence in soil bacteria.
format article
author Kaihuai Li
Gaoge Xu
Bo Wang
Guichun Wu
Rongxian Hou
Fengquan Liu
author_facet Kaihuai Li
Gaoge Xu
Bo Wang
Guichun Wu
Rongxian Hou
Fengquan Liu
author_sort Kaihuai Li
title The predatory soil bacterium Lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-GMP-independent manner
title_short The predatory soil bacterium Lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-GMP-independent manner
title_full The predatory soil bacterium Lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-GMP-independent manner
title_fullStr The predatory soil bacterium Lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-GMP-independent manner
title_full_unstemmed The predatory soil bacterium Lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-GMP-independent manner
title_sort predatory soil bacterium lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-gmp-independent manner
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/d0162b4a46e54e06ac7c7180f74386da
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