Allergic diseases attributable to atopy in a population sample of Asian children

Abstract The proportion of allergic diseases attributable to atopy remains a subject of controversy. This study aimed to estimate the population risk of physician-diagnosed asthma, rhinitis and eczema attributed to atopy among a population sample of Asian school-age children. Asian children aged 5–1...

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Autores principales:	Chao-Yi Wu, Hsin-Yi Huang, Wen-Chi Pan, Sui-Ling Liao, Man-Chin Hua, Ming-Han Tsai, Shen-Hao Lai, Kuo-Wei Yeh, Li-Chen Chen, Jing-Long Huang, Tsung-Chieh Yao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d023d211ee6641b5b949ef4f189c5621
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spelling	oai:doaj.org-article:d023d211ee6641b5b949ef4f189c56212021-12-02T16:35:36ZAllergic diseases attributable to atopy in a population sample of Asian children10.1038/s41598-021-95579-22045-2322https://doaj.org/article/d023d211ee6641b5b949ef4f189c56212021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95579-2https://doaj.org/toc/2045-2322Abstract The proportion of allergic diseases attributable to atopy remains a subject of controversy. This study aimed to estimate the population risk of physician-diagnosed asthma, rhinitis and eczema attributed to atopy among a population sample of Asian school-age children. Asian children aged 5–18 years (n = 1321) in the Prediction of Allergies in Taiwanese CHildren (PATCH) study were tested for serum allergen-specific immunoglobulin E. Physician-diagnosed asthma, rhinitis and eczema were assessed by a modified International Study of Asthma and Allergies in Childhood questionnaire. Atopy was defined as the presence of serum allergen-specific immunoglobulin E. In this population-based study, 50.4% of the subjects with asthma, 46.3% with rhinitis, and 46.7% with eczema were attributable to atopy. The population attributable risk (PAR) of atopy for three allergic diseases was higher in adolescents (asthma, 54.4%; rhinitis, 59.6%; eczema, 49.5%) than younger children aged less than 10 years (asthma, 46.9%; rhinitis, 39.5%; eczema, 41.9%). Among the seven allergen categories, sensitization to mites had the highest PARs for all three allergic diseases (51.3 to 64.1%), followed by sensitization to foods (asthma, 7.1%; rhinitis, 10.4%; eczema 27.7%). In conclusion, approximately half (46.3 to 50.4%) of Asian children in Taiwan with allergic diseases are attributable to atopy.Chao-Yi WuHsin-Yi HuangWen-Chi PanSui-Ling LiaoMan-Chin HuaMing-Han TsaiShen-Hao LaiKuo-Wei YehLi-Chen ChenJing-Long HuangTsung-Chieh YaoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Chao-Yi Wu Hsin-Yi Huang Wen-Chi Pan Sui-Ling Liao Man-Chin Hua Ming-Han Tsai Shen-Hao Lai Kuo-Wei Yeh Li-Chen Chen Jing-Long Huang Tsung-Chieh Yao Allergic diseases attributable to atopy in a population sample of Asian children
description	Abstract The proportion of allergic diseases attributable to atopy remains a subject of controversy. This study aimed to estimate the population risk of physician-diagnosed asthma, rhinitis and eczema attributed to atopy among a population sample of Asian school-age children. Asian children aged 5–18 years (n = 1321) in the Prediction of Allergies in Taiwanese CHildren (PATCH) study were tested for serum allergen-specific immunoglobulin E. Physician-diagnosed asthma, rhinitis and eczema were assessed by a modified International Study of Asthma and Allergies in Childhood questionnaire. Atopy was defined as the presence of serum allergen-specific immunoglobulin E. In this population-based study, 50.4% of the subjects with asthma, 46.3% with rhinitis, and 46.7% with eczema were attributable to atopy. The population attributable risk (PAR) of atopy for three allergic diseases was higher in adolescents (asthma, 54.4%; rhinitis, 59.6%; eczema, 49.5%) than younger children aged less than 10 years (asthma, 46.9%; rhinitis, 39.5%; eczema, 41.9%). Among the seven allergen categories, sensitization to mites had the highest PARs for all three allergic diseases (51.3 to 64.1%), followed by sensitization to foods (asthma, 7.1%; rhinitis, 10.4%; eczema 27.7%). In conclusion, approximately half (46.3 to 50.4%) of Asian children in Taiwan with allergic diseases are attributable to atopy.
format	article
author	Chao-Yi Wu Hsin-Yi Huang Wen-Chi Pan Sui-Ling Liao Man-Chin Hua Ming-Han Tsai Shen-Hao Lai Kuo-Wei Yeh Li-Chen Chen Jing-Long Huang Tsung-Chieh Yao
author_facet	Chao-Yi Wu Hsin-Yi Huang Wen-Chi Pan Sui-Ling Liao Man-Chin Hua Ming-Han Tsai Shen-Hao Lai Kuo-Wei Yeh Li-Chen Chen Jing-Long Huang Tsung-Chieh Yao
author_sort	Chao-Yi Wu
title	Allergic diseases attributable to atopy in a population sample of Asian children
title_short	Allergic diseases attributable to atopy in a population sample of Asian children
title_full	Allergic diseases attributable to atopy in a population sample of Asian children
title_fullStr	Allergic diseases attributable to atopy in a population sample of Asian children
title_full_unstemmed	Allergic diseases attributable to atopy in a population sample of Asian children
title_sort	allergic diseases attributable to atopy in a population sample of asian children
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d023d211ee6641b5b949ef4f189c5621
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Allergic diseases attributable to atopy in a population sample of Asian children

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