Does amantadine induce acute psychosis? A case report and literature review

Wei-juan Xu,1,2 Ning Wei,1,2 Yi Xu,1,2 Shao-hua Hu1,2 1Department of Psychiatry, The First Affiliated Hospital of Zhejiang University School of Medicine, 2The Key Laboratory of Mental Disorder’s Management of Zhejiang Province, Hangzhou, People’s Republic of China Background: O...

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Autores principales:	Xu WJ, Wei N, Xu Y, Hu SH
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	Amantadine Acetaminophen Psychosis Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/d028dc2e13364c01b83cacc0cf4a2b22
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spelling	oai:doaj.org-article:d028dc2e13364c01b83cacc0cf4a2b222021-12-02T02:19:41ZDoes amantadine induce acute psychosis? A case report and literature review1178-2021https://doaj.org/article/d028dc2e13364c01b83cacc0cf4a2b222016-04-01T00:00:00Zhttps://www.dovepress.com/does-amantadine-induce-acute-psychosis-a-case-report-and-literature-re-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Wei-juan Xu,1,2 Ning Wei,1,2 Yi Xu,1,2 Shao-hua Hu1,2 1Department of Psychiatry, The First Affiliated Hospital of Zhejiang University School of Medicine, 2The Key Laboratory of Mental Disorder’s Management of Zhejiang Province, Hangzhou, People’s Republic of China Background: Over-the-counter cold medicines, which contain amantadine, are widely used in the People’s Republic of China. Clinicians are familiar with the psychosis caused by long-term treatment with amantadine, especially in elderly patients; however, early-onset psychotic complications among healthy young individuals have rarely been reported. Case presentation: This article reports the case of a 28-year-old patient who presented with hallucination–delusion syndrome soon after treatment with cold medicine containing amantadine hydrochloride and acetaminophen. The symptoms resolved completely after a 2-week course of paliperidone treatment. Conclusion: Clinicians should be sensitive to the acute psychotic complications induced by an interaction between amantadine and acetaminophen. Keywords: amantadine, acetaminophen, side effectsXu WJWei NXu YHu SHDove Medical PressarticleAmantadine Acetaminophen PsychosisNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2016, Iss Issue 1, Pp 781-783 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Amantadine Acetaminophen Psychosis Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Amantadine Acetaminophen Psychosis Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Xu WJ Wei N Xu Y Hu SH Does amantadine induce acute psychosis? A case report and literature review
description	Wei-juan Xu,1,2 Ning Wei,1,2 Yi Xu,1,2 Shao-hua Hu1,2 1Department of Psychiatry, The First Affiliated Hospital of Zhejiang University School of Medicine, 2The Key Laboratory of Mental Disorder’s Management of Zhejiang Province, Hangzhou, People’s Republic of China Background: Over-the-counter cold medicines, which contain amantadine, are widely used in the People’s Republic of China. Clinicians are familiar with the psychosis caused by long-term treatment with amantadine, especially in elderly patients; however, early-onset psychotic complications among healthy young individuals have rarely been reported. Case presentation: This article reports the case of a 28-year-old patient who presented with hallucination–delusion syndrome soon after treatment with cold medicine containing amantadine hydrochloride and acetaminophen. The symptoms resolved completely after a 2-week course of paliperidone treatment. Conclusion: Clinicians should be sensitive to the acute psychotic complications induced by an interaction between amantadine and acetaminophen. Keywords: amantadine, acetaminophen, side effects
format	article
author	Xu WJ Wei N Xu Y Hu SH
author_facet	Xu WJ Wei N Xu Y Hu SH
author_sort	Xu WJ
title	Does amantadine induce acute psychosis? A case report and literature review
title_short	Does amantadine induce acute psychosis? A case report and literature review
title_full	Does amantadine induce acute psychosis? A case report and literature review
title_fullStr	Does amantadine induce acute psychosis? A case report and literature review
title_full_unstemmed	Does amantadine induce acute psychosis? A case report and literature review
title_sort	does amantadine induce acute psychosis? a case report and literature review
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/d028dc2e13364c01b83cacc0cf4a2b22
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Does amantadine induce acute psychosis? A case report and literature review

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