Cancer associated aberrant protein O-glycosylation can modify antigen processing and immune response.

Aberrant glycosylation of mucins and other extracellular proteins is an important event in carcinogenesis and the resulting cancer associated glycans have been suggested as targets in cancer immunotherapy. We assessed the role of O-linked GalNAc glycosylation on antigen uptake, processing, and prese...

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Autores principales: Caroline B Madsen, Cecilie Petersen, Kirstine Lavrsen, Mikkel Harndahl, Søren Buus, Henrik Clausen, Anders E Pedersen, Hans H Wandall
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/d02991980215470ebc500f26e83a22fc
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