Effect of comorbid mood and anxiety disorders on breast and cervical cancer screening in immune-mediated inflammatory disease.
We aimed to examine rates of breast and cervical cancer screening in women with immune-mediated inflammatory diseases (IMID), including inflammatory bowel disease (IBD), multiple sclerosis (MS) and rheumatoid arthritis (RA) versus a matched cohort with IMID; and examine the association of psychiatri...
Guardado en:
| Autores principales: | , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Public Library of Science (PLoS)
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/d042c2aa90b645e6b9dcc53432cba228 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:d042c2aa90b645e6b9dcc53432cba228 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:d042c2aa90b645e6b9dcc53432cba2282021-12-02T20:15:15ZEffect of comorbid mood and anxiety disorders on breast and cervical cancer screening in immune-mediated inflammatory disease.1932-620310.1371/journal.pone.0249809https://doaj.org/article/d042c2aa90b645e6b9dcc53432cba2282021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0249809https://doaj.org/toc/1932-6203We aimed to examine rates of breast and cervical cancer screening in women with immune-mediated inflammatory diseases (IMID), including inflammatory bowel disease (IBD), multiple sclerosis (MS) and rheumatoid arthritis (RA) versus a matched cohort with IMID; and examine the association of psychiatric comorbidity with screening in these populations. We conducted a retrospective cohort study in Manitoba, Canada using administrative data. We identified women with IBD, MS and RA, and controls without these IMID matched on age and region. Annually, we identified individuals with any active mood/anxiety disorder. Using physician claims, we determined the proportion of each cohort who had cervical cancer screening within three-year intervals, and mammography screening within two-year intervals. We modeled the difference in the proportion of the IMID and matched cohorts who underwent mammography; and pap tests using log-binomial regression with generalized estimating equations, adjusting for sociodemographics, comorbidity and immune therapy use. We tested for additive interactions between cohort and mood/anxiety disorder status. During 2006-2016, we identified 17,230 women with IMID (4,623 with IBD, 3,399 with MS, and 9,458 with RA) and 85,349 matched controls. Having an IMID was associated with lower (-1%) use of mammography; however, this reflected a mixture of more mammography in the IBD cohort (+2.9%) and less mammography in the MS (-4.8 to -5.2%) and RA (-1.5%) cohorts. Within the IBD, MS and RA cohorts, having an active mood/anxiety disorder was associated with more mammography use than having an inactive mood/anxiety disorder. The MS and RA cohorts were less likely to undergo Pap testing than their matched cohorts. In the absence of an active mood/anxiety disorder, the IBD cohort was more likely to undergo Pap testing than its matched cohort; the opposite was true when an active mood/anxiety disorder was present. Among women with an IMID, mood/anxiety disorder influence participation in cancer screening.Ruth Ann MarrieRandy WalldJames M BoltonJitender SareenScott B PattenAlexander SingerLisa M LixCarol A HitchonJames J MarriottRenée El-GabalawyAlan KatzJohn D FiskCharles N BernsteinCIHR Team in Defining the Burden and Managing the Effects of Psychiatric Comorbidity in Chronic Immunoinflammatory DiseasePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0249809 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine R Science Q |
| spellingShingle |
Medicine R Science Q Ruth Ann Marrie Randy Walld James M Bolton Jitender Sareen Scott B Patten Alexander Singer Lisa M Lix Carol A Hitchon James J Marriott Renée El-Gabalawy Alan Katz John D Fisk Charles N Bernstein CIHR Team in Defining the Burden and Managing the Effects of Psychiatric Comorbidity in Chronic Immunoinflammatory Disease Effect of comorbid mood and anxiety disorders on breast and cervical cancer screening in immune-mediated inflammatory disease. |
| description |
We aimed to examine rates of breast and cervical cancer screening in women with immune-mediated inflammatory diseases (IMID), including inflammatory bowel disease (IBD), multiple sclerosis (MS) and rheumatoid arthritis (RA) versus a matched cohort with IMID; and examine the association of psychiatric comorbidity with screening in these populations. We conducted a retrospective cohort study in Manitoba, Canada using administrative data. We identified women with IBD, MS and RA, and controls without these IMID matched on age and region. Annually, we identified individuals with any active mood/anxiety disorder. Using physician claims, we determined the proportion of each cohort who had cervical cancer screening within three-year intervals, and mammography screening within two-year intervals. We modeled the difference in the proportion of the IMID and matched cohorts who underwent mammography; and pap tests using log-binomial regression with generalized estimating equations, adjusting for sociodemographics, comorbidity and immune therapy use. We tested for additive interactions between cohort and mood/anxiety disorder status. During 2006-2016, we identified 17,230 women with IMID (4,623 with IBD, 3,399 with MS, and 9,458 with RA) and 85,349 matched controls. Having an IMID was associated with lower (-1%) use of mammography; however, this reflected a mixture of more mammography in the IBD cohort (+2.9%) and less mammography in the MS (-4.8 to -5.2%) and RA (-1.5%) cohorts. Within the IBD, MS and RA cohorts, having an active mood/anxiety disorder was associated with more mammography use than having an inactive mood/anxiety disorder. The MS and RA cohorts were less likely to undergo Pap testing than their matched cohorts. In the absence of an active mood/anxiety disorder, the IBD cohort was more likely to undergo Pap testing than its matched cohort; the opposite was true when an active mood/anxiety disorder was present. Among women with an IMID, mood/anxiety disorder influence participation in cancer screening. |
| format |
article |
| author |
Ruth Ann Marrie Randy Walld James M Bolton Jitender Sareen Scott B Patten Alexander Singer Lisa M Lix Carol A Hitchon James J Marriott Renée El-Gabalawy Alan Katz John D Fisk Charles N Bernstein CIHR Team in Defining the Burden and Managing the Effects of Psychiatric Comorbidity in Chronic Immunoinflammatory Disease |
| author_facet |
Ruth Ann Marrie Randy Walld James M Bolton Jitender Sareen Scott B Patten Alexander Singer Lisa M Lix Carol A Hitchon James J Marriott Renée El-Gabalawy Alan Katz John D Fisk Charles N Bernstein CIHR Team in Defining the Burden and Managing the Effects of Psychiatric Comorbidity in Chronic Immunoinflammatory Disease |
| author_sort |
Ruth Ann Marrie |
| title |
Effect of comorbid mood and anxiety disorders on breast and cervical cancer screening in immune-mediated inflammatory disease. |
| title_short |
Effect of comorbid mood and anxiety disorders on breast and cervical cancer screening in immune-mediated inflammatory disease. |
| title_full |
Effect of comorbid mood and anxiety disorders on breast and cervical cancer screening in immune-mediated inflammatory disease. |
| title_fullStr |
Effect of comorbid mood and anxiety disorders on breast and cervical cancer screening in immune-mediated inflammatory disease. |
| title_full_unstemmed |
Effect of comorbid mood and anxiety disorders on breast and cervical cancer screening in immune-mediated inflammatory disease. |
| title_sort |
effect of comorbid mood and anxiety disorders on breast and cervical cancer screening in immune-mediated inflammatory disease. |
| publisher |
Public Library of Science (PLoS) |
| publishDate |
2021 |
| url |
https://doaj.org/article/d042c2aa90b645e6b9dcc53432cba228 |
| work_keys_str_mv |
AT ruthannmarrie effectofcomorbidmoodandanxietydisordersonbreastandcervicalcancerscreeninginimmunemediatedinflammatorydisease AT randywalld effectofcomorbidmoodandanxietydisordersonbreastandcervicalcancerscreeninginimmunemediatedinflammatorydisease AT jamesmbolton effectofcomorbidmoodandanxietydisordersonbreastandcervicalcancerscreeninginimmunemediatedinflammatorydisease AT jitendersareen effectofcomorbidmoodandanxietydisordersonbreastandcervicalcancerscreeninginimmunemediatedinflammatorydisease AT scottbpatten effectofcomorbidmoodandanxietydisordersonbreastandcervicalcancerscreeninginimmunemediatedinflammatorydisease AT alexandersinger effectofcomorbidmoodandanxietydisordersonbreastandcervicalcancerscreeninginimmunemediatedinflammatorydisease AT lisamlix effectofcomorbidmoodandanxietydisordersonbreastandcervicalcancerscreeninginimmunemediatedinflammatorydisease AT carolahitchon effectofcomorbidmoodandanxietydisordersonbreastandcervicalcancerscreeninginimmunemediatedinflammatorydisease AT jamesjmarriott effectofcomorbidmoodandanxietydisordersonbreastandcervicalcancerscreeninginimmunemediatedinflammatorydisease AT reneeelgabalawy effectofcomorbidmoodandanxietydisordersonbreastandcervicalcancerscreeninginimmunemediatedinflammatorydisease AT alankatz effectofcomorbidmoodandanxietydisordersonbreastandcervicalcancerscreeninginimmunemediatedinflammatorydisease AT johndfisk effectofcomorbidmoodandanxietydisordersonbreastandcervicalcancerscreeninginimmunemediatedinflammatorydisease AT charlesnbernstein effectofcomorbidmoodandanxietydisordersonbreastandcervicalcancerscreeninginimmunemediatedinflammatorydisease AT cihrteamindefiningtheburdenandmanagingtheeffectsofpsychiatriccomorbidityinchronicimmunoinflammatorydisease effectofcomorbidmoodandanxietydisordersonbreastandcervicalcancerscreeninginimmunemediatedinflammatorydisease |
| _version_ |
1718374610921062400 |