Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
Atherosclerosis is a chronic, progressive disease which eventually leads to coronary heart disease (CHD), ischemic stroke and other atherosclerotic cardiovascular disease (ASCVD). Numerous studies have demonstrated an atherogenic role of oxidized low-density lipoprotein (ox-LDL) in the progression o...
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KeAi Communications Co., Ltd.
2017
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oai:doaj.org-article:d049b812b424462083469c72b873f9362021-12-02T14:11:50ZAssociation between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease2095-882X10.1016/j.cdtm.2017.02.008https://doaj.org/article/d049b812b424462083469c72b873f9362017-06-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095882X16301244https://doaj.org/toc/2095-882XAtherosclerosis is a chronic, progressive disease which eventually leads to coronary heart disease (CHD), ischemic stroke and other atherosclerotic cardiovascular disease (ASCVD). Numerous studies have demonstrated an atherogenic role of oxidized low-density lipoprotein (ox-LDL) in the progression of ASCVD. This article briefly reviews the atherogenic mechanism of ox-LDL, the methods of measuring ox-LDL in the circulation, effect of medical therapy and life-style modification on ox-LDL level, and the association between circulating ox-LDL and atherosclerosis, including clinical ASCVD events and subclinical atherosclerosis, in observational studies. Keywords: Oxidized low density lipoprotein, Atherosclerosis, Cardiovascular disease, Subclinical atherosclerosis, ReviewShen GaoJing LiuKeAi Communications Co., Ltd.articleMedicine (General)R5-920ENChronic Diseases and Translational Medicine, Vol 3, Iss 2, Pp 89-94 (2017) |
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Medicine (General) R5-920 |
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Medicine (General) R5-920 Shen Gao Jing Liu Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease |
description |
Atherosclerosis is a chronic, progressive disease which eventually leads to coronary heart disease (CHD), ischemic stroke and other atherosclerotic cardiovascular disease (ASCVD). Numerous studies have demonstrated an atherogenic role of oxidized low-density lipoprotein (ox-LDL) in the progression of ASCVD. This article briefly reviews the atherogenic mechanism of ox-LDL, the methods of measuring ox-LDL in the circulation, effect of medical therapy and life-style modification on ox-LDL level, and the association between circulating ox-LDL and atherosclerosis, including clinical ASCVD events and subclinical atherosclerosis, in observational studies. Keywords: Oxidized low density lipoprotein, Atherosclerosis, Cardiovascular disease, Subclinical atherosclerosis, Review |
format |
article |
author |
Shen Gao Jing Liu |
author_facet |
Shen Gao Jing Liu |
author_sort |
Shen Gao |
title |
Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease |
title_short |
Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease |
title_full |
Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease |
title_fullStr |
Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease |
title_full_unstemmed |
Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease |
title_sort |
association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease |
publisher |
KeAi Communications Co., Ltd. |
publishDate |
2017 |
url |
https://doaj.org/article/d049b812b424462083469c72b873f936 |
work_keys_str_mv |
AT shengao associationbetweencirculatingoxidizedlowdensitylipoproteinandatheroscleroticcardiovasculardisease AT jingliu associationbetweencirculatingoxidizedlowdensitylipoproteinandatheroscleroticcardiovasculardisease |
_version_ |
1718391871274745856 |