Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease

Atherosclerosis is a chronic, progressive disease which eventually leads to coronary heart disease (CHD), ischemic stroke and other atherosclerotic cardiovascular disease (ASCVD). Numerous studies have demonstrated an atherogenic role of oxidized low-density lipoprotein (ox-LDL) in the progression o...

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Autores principales: Shen Gao, Jing Liu
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Lenguaje:EN
Publicado: KeAi Communications Co., Ltd. 2017
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Acceso en línea:https://doaj.org/article/d049b812b424462083469c72b873f936
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spelling oai:doaj.org-article:d049b812b424462083469c72b873f9362021-12-02T14:11:50ZAssociation between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease2095-882X10.1016/j.cdtm.2017.02.008https://doaj.org/article/d049b812b424462083469c72b873f9362017-06-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095882X16301244https://doaj.org/toc/2095-882XAtherosclerosis is a chronic, progressive disease which eventually leads to coronary heart disease (CHD), ischemic stroke and other atherosclerotic cardiovascular disease (ASCVD). Numerous studies have demonstrated an atherogenic role of oxidized low-density lipoprotein (ox-LDL) in the progression of ASCVD. This article briefly reviews the atherogenic mechanism of ox-LDL, the methods of measuring ox-LDL in the circulation, effect of medical therapy and life-style modification on ox-LDL level, and the association between circulating ox-LDL and atherosclerosis, including clinical ASCVD events and subclinical atherosclerosis, in observational studies. Keywords: Oxidized low density lipoprotein, Atherosclerosis, Cardiovascular disease, Subclinical atherosclerosis, ReviewShen GaoJing LiuKeAi Communications Co., Ltd.articleMedicine (General)R5-920ENChronic Diseases and Translational Medicine, Vol 3, Iss 2, Pp 89-94 (2017)
institution DOAJ
collection DOAJ
language EN
topic Medicine (General)
R5-920
spellingShingle Medicine (General)
R5-920
Shen Gao
Jing Liu
Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
description Atherosclerosis is a chronic, progressive disease which eventually leads to coronary heart disease (CHD), ischemic stroke and other atherosclerotic cardiovascular disease (ASCVD). Numerous studies have demonstrated an atherogenic role of oxidized low-density lipoprotein (ox-LDL) in the progression of ASCVD. This article briefly reviews the atherogenic mechanism of ox-LDL, the methods of measuring ox-LDL in the circulation, effect of medical therapy and life-style modification on ox-LDL level, and the association between circulating ox-LDL and atherosclerosis, including clinical ASCVD events and subclinical atherosclerosis, in observational studies. Keywords: Oxidized low density lipoprotein, Atherosclerosis, Cardiovascular disease, Subclinical atherosclerosis, Review
format article
author Shen Gao
Jing Liu
author_facet Shen Gao
Jing Liu
author_sort Shen Gao
title Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
title_short Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
title_full Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
title_fullStr Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
title_full_unstemmed Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
title_sort association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
publisher KeAi Communications Co., Ltd.
publishDate 2017
url https://doaj.org/article/d049b812b424462083469c72b873f936
work_keys_str_mv AT shengao associationbetweencirculatingoxidizedlowdensitylipoproteinandatheroscleroticcardiovasculardisease
AT jingliu associationbetweencirculatingoxidizedlowdensitylipoproteinandatheroscleroticcardiovasculardisease
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