A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast
Transcription of lncRNAs is known to regulate local gene expression. Here the authors describe how orchestrated transcription of two contiguous lncRNAs facilitates a regulatory circuit by which the master regulator for entry into meiosis, IME1, directs the decision to enter meiosis in yeast.
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Nature Portfolio
2018
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oai:doaj.org-article:d06124a5d36c4c2e86bd0405269e78812021-12-02T17:33:18ZA regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast10.1038/s41467-018-03213-z2041-1723https://doaj.org/article/d06124a5d36c4c2e86bd0405269e78812018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03213-zhttps://doaj.org/toc/2041-1723Transcription of lncRNAs is known to regulate local gene expression. Here the authors describe how orchestrated transcription of two contiguous lncRNAs facilitates a regulatory circuit by which the master regulator for entry into meiosis, IME1, directs the decision to enter meiosis in yeast.Fabien MorettoN. Ezgi WoodGavin KellyAndreas DoncicFolkert J. van WervenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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DOAJ |
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EN |
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Science Q |
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Science Q Fabien Moretto N. Ezgi Wood Gavin Kelly Andreas Doncic Folkert J. van Werven A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast |
description |
Transcription of lncRNAs is known to regulate local gene expression. Here the authors describe how orchestrated transcription of two contiguous lncRNAs facilitates a regulatory circuit by which the master regulator for entry into meiosis, IME1, directs the decision to enter meiosis in yeast. |
format |
article |
author |
Fabien Moretto N. Ezgi Wood Gavin Kelly Andreas Doncic Folkert J. van Werven |
author_facet |
Fabien Moretto N. Ezgi Wood Gavin Kelly Andreas Doncic Folkert J. van Werven |
author_sort |
Fabien Moretto |
title |
A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast |
title_short |
A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast |
title_full |
A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast |
title_fullStr |
A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast |
title_full_unstemmed |
A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast |
title_sort |
regulatory circuit of two lncrnas and a master regulator directs cell fate in yeast |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/d06124a5d36c4c2e86bd0405269e7881 |
work_keys_str_mv |
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