A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast

Transcription of lncRNAs is known to regulate local gene expression. Here the authors describe how orchestrated transcription of two contiguous lncRNAs facilitates a regulatory circuit by which the master regulator for entry into meiosis, IME1, directs the decision to enter meiosis in yeast.

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Autores principales: Fabien Moretto, N. Ezgi Wood, Gavin Kelly, Andreas Doncic, Folkert J. van Werven
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/d06124a5d36c4c2e86bd0405269e7881
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spelling oai:doaj.org-article:d06124a5d36c4c2e86bd0405269e78812021-12-02T17:33:18ZA regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast10.1038/s41467-018-03213-z2041-1723https://doaj.org/article/d06124a5d36c4c2e86bd0405269e78812018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03213-zhttps://doaj.org/toc/2041-1723Transcription of lncRNAs is known to regulate local gene expression. Here the authors describe how orchestrated transcription of two contiguous lncRNAs facilitates a regulatory circuit by which the master regulator for entry into meiosis, IME1, directs the decision to enter meiosis in yeast.Fabien MorettoN. Ezgi WoodGavin KellyAndreas DoncicFolkert J. van WervenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Fabien Moretto
N. Ezgi Wood
Gavin Kelly
Andreas Doncic
Folkert J. van Werven
A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast
description Transcription of lncRNAs is known to regulate local gene expression. Here the authors describe how orchestrated transcription of two contiguous lncRNAs facilitates a regulatory circuit by which the master regulator for entry into meiosis, IME1, directs the decision to enter meiosis in yeast.
format article
author Fabien Moretto
N. Ezgi Wood
Gavin Kelly
Andreas Doncic
Folkert J. van Werven
author_facet Fabien Moretto
N. Ezgi Wood
Gavin Kelly
Andreas Doncic
Folkert J. van Werven
author_sort Fabien Moretto
title A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast
title_short A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast
title_full A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast
title_fullStr A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast
title_full_unstemmed A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast
title_sort regulatory circuit of two lncrnas and a master regulator directs cell fate in yeast
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/d06124a5d36c4c2e86bd0405269e7881
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