Capturing cell type-specific chromatin compartment patterns by applying topic modeling to single-cell Hi-C data.

Capturing cell type-specific chromatin compartment patterns by applying topic modeling to single-cell Hi-C data.

Single-cell Hi-C (scHi-C) interrogates genome-wide chromatin interaction in individual cells, allowing us to gain insights into 3D genome organization. However, the extremely sparse nature of scHi-C data poses a significant barrier to analysis, limiting our ability to tease out hidden biological inf...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Hyeon-Jin Kim, Galip Gürkan Yardımcı, Giancarlo Bonora, Vijay Ramani, Jie Liu, Ruolan Qiu, Choli Lee, Jennifer Hesson, Carol B Ware, Jay Shendure, Zhijun Duan, William Stafford Noble
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2020
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/d087140ff4c3496697afe98471225fab
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares