Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae

Leprosy is caused by the yet-uncultured pathogen Mycobacterium leprae. Here, Benjak et al. obtain M. leprae genome sequences from DNA extracted from patients' skin biopsies and, by analysing 154 genomes from 25 countries, provide insight into the pathogen’s evolution and antimicrobial resistanc...

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Autores principales: Andrej Benjak, Charlotte Avanzi, Pushpendra Singh, Chloé Loiseau, Selfu Girma, Philippe Busso, Amanda N. Brum Fontes, Yuji Miyamoto, Masako Namisato, Kidist Bobosha, Claudio G. Salgado, Moisés B. da Silva, Raquel C. Bouth, Marco A. C. Frade, Fred Bernardes Filho, Josafá G. Barreto, José A. C. Nery, Samira Bührer-Sékula, Andréanne Lupien, Abdul R. Al-Samie, Yasin Al-Qubati, Abdul S. Alkubati, Gisela Bretzel, Lucio Vera-Cabrera, Fatoumata Sakho, Christian R. Johnson, Mamoudou Kodio, Abdoulaye Fomba, Samba O. Sow, Moussa Gado, Ousmane Konaté, Mariane M. A. Stefani, Gerson O. Penna, Philip N. Suffys, Euzenir Nunes Sarno, Milton O. Moraes, Patricia S. Rosa, Ida M. F. Dias Baptista, John S. Spencer, Abraham Aseffa, Masanori Matsuoka, Masanori Kai, Stewart T. Cole
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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spelling oai:doaj.org-article:d0872b16248e40f0a1f5adae60f931762021-12-02T14:38:52ZPhylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae10.1038/s41467-017-02576-z2041-1723https://doaj.org/article/d0872b16248e40f0a1f5adae60f931762018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02576-zhttps://doaj.org/toc/2041-1723Leprosy is caused by the yet-uncultured pathogen Mycobacterium leprae. Here, Benjak et al. obtain M. leprae genome sequences from DNA extracted from patients' skin biopsies and, by analysing 154 genomes from 25 countries, provide insight into the pathogen’s evolution and antimicrobial resistance.Andrej BenjakCharlotte AvanziPushpendra SinghChloé LoiseauSelfu GirmaPhilippe BussoAmanda N. Brum FontesYuji MiyamotoMasako NamisatoKidist BoboshaClaudio G. SalgadoMoisés B. da SilvaRaquel C. BouthMarco A. C. FradeFred Bernardes FilhoJosafá G. BarretoJosé A. C. NerySamira Bührer-SékulaAndréanne LupienAbdul R. Al-SamieYasin Al-QubatiAbdul S. AlkubatiGisela BretzelLucio Vera-CabreraFatoumata SakhoChristian R. JohnsonMamoudou KodioAbdoulaye FombaSamba O. SowMoussa GadoOusmane KonatéMariane M. A. StefaniGerson O. PennaPhilip N. SuffysEuzenir Nunes SarnoMilton O. MoraesPatricia S. RosaIda M. F. Dias BaptistaJohn S. SpencerAbraham AseffaMasanori MatsuokaMasanori KaiStewart T. ColeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Andrej Benjak
Charlotte Avanzi
Pushpendra Singh
Chloé Loiseau
Selfu Girma
Philippe Busso
Amanda N. Brum Fontes
Yuji Miyamoto
Masako Namisato
Kidist Bobosha
Claudio G. Salgado
Moisés B. da Silva
Raquel C. Bouth
Marco A. C. Frade
Fred Bernardes Filho
Josafá G. Barreto
José A. C. Nery
Samira Bührer-Sékula
Andréanne Lupien
Abdul R. Al-Samie
Yasin Al-Qubati
Abdul S. Alkubati
Gisela Bretzel
Lucio Vera-Cabrera
Fatoumata Sakho
Christian R. Johnson
Mamoudou Kodio
Abdoulaye Fomba
Samba O. Sow
Moussa Gado
Ousmane Konaté
Mariane M. A. Stefani
Gerson O. Penna
Philip N. Suffys
Euzenir Nunes Sarno
Milton O. Moraes
Patricia S. Rosa
Ida M. F. Dias Baptista
John S. Spencer
Abraham Aseffa
Masanori Matsuoka
Masanori Kai
Stewart T. Cole
Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae
description Leprosy is caused by the yet-uncultured pathogen Mycobacterium leprae. Here, Benjak et al. obtain M. leprae genome sequences from DNA extracted from patients' skin biopsies and, by analysing 154 genomes from 25 countries, provide insight into the pathogen’s evolution and antimicrobial resistance.
format article
author Andrej Benjak
Charlotte Avanzi
Pushpendra Singh
Chloé Loiseau
Selfu Girma
Philippe Busso
Amanda N. Brum Fontes
Yuji Miyamoto
Masako Namisato
Kidist Bobosha
Claudio G. Salgado
Moisés B. da Silva
Raquel C. Bouth
Marco A. C. Frade
Fred Bernardes Filho
Josafá G. Barreto
José A. C. Nery
Samira Bührer-Sékula
Andréanne Lupien
Abdul R. Al-Samie
Yasin Al-Qubati
Abdul S. Alkubati
Gisela Bretzel
Lucio Vera-Cabrera
Fatoumata Sakho
Christian R. Johnson
Mamoudou Kodio
Abdoulaye Fomba
Samba O. Sow
Moussa Gado
Ousmane Konaté
Mariane M. A. Stefani
Gerson O. Penna
Philip N. Suffys
Euzenir Nunes Sarno
Milton O. Moraes
Patricia S. Rosa
Ida M. F. Dias Baptista
John S. Spencer
Abraham Aseffa
Masanori Matsuoka
Masanori Kai
Stewart T. Cole
author_facet Andrej Benjak
Charlotte Avanzi
Pushpendra Singh
Chloé Loiseau
Selfu Girma
Philippe Busso
Amanda N. Brum Fontes
Yuji Miyamoto
Masako Namisato
Kidist Bobosha
Claudio G. Salgado
Moisés B. da Silva
Raquel C. Bouth
Marco A. C. Frade
Fred Bernardes Filho
Josafá G. Barreto
José A. C. Nery
Samira Bührer-Sékula
Andréanne Lupien
Abdul R. Al-Samie
Yasin Al-Qubati
Abdul S. Alkubati
Gisela Bretzel
Lucio Vera-Cabrera
Fatoumata Sakho
Christian R. Johnson
Mamoudou Kodio
Abdoulaye Fomba
Samba O. Sow
Moussa Gado
Ousmane Konaté
Mariane M. A. Stefani
Gerson O. Penna
Philip N. Suffys
Euzenir Nunes Sarno
Milton O. Moraes
Patricia S. Rosa
Ida M. F. Dias Baptista
John S. Spencer
Abraham Aseffa
Masanori Matsuoka
Masanori Kai
Stewart T. Cole
author_sort Andrej Benjak
title Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae
title_short Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae
title_full Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae
title_fullStr Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae
title_full_unstemmed Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae
title_sort phylogenomics and antimicrobial resistance of the leprosy bacillus mycobacterium leprae
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/d0872b16248e40f0a1f5adae60f93176
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