Inhibition of competence development, horizontal gene transfer and virulence in Streptococcus pneumoniae by a modified competence stimulating peptide.

Competence stimulating peptide (CSP) is a 17-amino acid peptide pheromone secreted by Streptococcus pneumoniae. Upon binding of CSP to its membrane-associated receptor kinase ComD, a cascade of signaling events is initiated, leading to activation of the competence regulon by the response regulator C...

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Bibliographic Details
Main Authors: Luchang Zhu, Gee W Lau
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
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Online Access:https://doaj.org/article/d09086c329ec4d13b60640648b3ee9e4
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