Orai1–STIM1 Regulates Increased Ca<sup>2+</sup> Mobilization, Leading to Contractile Duchenne Muscular Dystrophy Phenotypes in Patient-Derived Induced Pluripotent Stem Cells

Ca<sup>2+</sup> overload is one of the factors leading to Duchenne muscular dystrophy (DMD) pathogenesis. However, the molecular targets of dystrophin deficiency-dependent Ca<sup>2+</sup> overload and the correlation between Ca<sup>2+</sup> overload and contractil...

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Autores principales: Tomoya Uchimura, Hidetoshi Sakurai
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/d09301e338eb479ca80f3f40bd7f4477
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