Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina

The purpose of this study was to examine the association between neighborhood social deprivation and individual-level characteristics on breast cancer staging in African American and white breast cancer patients. We established a retrospective cohort of patients with breast cancer diagnosed from 199...

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Autores principales:	Oluwole Adeyemi Babatunde, Whitney E. Zahnd, Jan M. Eberth, Andrew B. Lawson, Swann Arp Adams, Eric Adjei Boakye, Melanie S. Jefferson, Caitlin G. Allen, John L. Pearce, Hong Li, Chanita Hughes Halbert
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	african american breast cancer social deprivation index (SDI) cancer stage race health disparities Medicine R
Acceso en línea:	https://doaj.org/article/d09404301d0542c8b0fe01380c07bcc9
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spelling	oai:doaj.org-article:d09404301d0542c8b0fe01380c07bcc92021-11-25T17:48:41ZAssociation between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina10.3390/ijerph1822118241660-46011661-7827https://doaj.org/article/d09404301d0542c8b0fe01380c07bcc92021-11-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/22/11824https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601The purpose of this study was to examine the association between neighborhood social deprivation and individual-level characteristics on breast cancer staging in African American and white breast cancer patients. We established a retrospective cohort of patients with breast cancer diagnosed from 1996 to 2015 using the South Carolina Central Cancer Registry. We abstracted sociodemographic and clinical variables from the registry and linked these data to a county-level composite that captured neighborhood social conditions—the social deprivation index (SDI). Data were analyzed using chi-square tests, Student’s <i>t</i>-test, and multivariable ordinal regression analysis to evaluate associations. The study sample included 52,803 female patients with breast cancer. Results from the multivariable ordinal regression model demonstrate that higher SDI (OR = 1.06, 95% CI: 1.02–1.10), African American race (OR = 1.35, 95% CI: 1.29–1.41), and being unmarried (OR = 1.17, 95% CI: 1.13–1.22) were associated with a distant stage at diagnosis. Higher tumor grade, younger age, and more recent year of diagnosis were also associated with distant-stage diagnosis. As a proxy for neighborhood context, the SDI can be used by cancer registries and related population-based studies to identify geographic areas that could be prioritized for cancer prevention and control efforts.Oluwole Adeyemi BabatundeWhitney E. ZahndJan M. EberthAndrew B. LawsonSwann Arp AdamsEric Adjei BoakyeMelanie S. JeffersonCaitlin G. AllenJohn L. PearceHong LiChanita Hughes HalbertMDPI AGarticleafrican americanbreast cancersocial deprivation index (SDI)cancer stageracehealth disparitiesMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 11824, p 11824 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	african american breast cancer social deprivation index (SDI) cancer stage race health disparities Medicine R
spellingShingle	african american breast cancer social deprivation index (SDI) cancer stage race health disparities Medicine R Oluwole Adeyemi Babatunde Whitney E. Zahnd Jan M. Eberth Andrew B. Lawson Swann Arp Adams Eric Adjei Boakye Melanie S. Jefferson Caitlin G. Allen John L. Pearce Hong Li Chanita Hughes Halbert Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina
description	The purpose of this study was to examine the association between neighborhood social deprivation and individual-level characteristics on breast cancer staging in African American and white breast cancer patients. We established a retrospective cohort of patients with breast cancer diagnosed from 1996 to 2015 using the South Carolina Central Cancer Registry. We abstracted sociodemographic and clinical variables from the registry and linked these data to a county-level composite that captured neighborhood social conditions—the social deprivation index (SDI). Data were analyzed using chi-square tests, Student’s <i>t</i>-test, and multivariable ordinal regression analysis to evaluate associations. The study sample included 52,803 female patients with breast cancer. Results from the multivariable ordinal regression model demonstrate that higher SDI (OR = 1.06, 95% CI: 1.02–1.10), African American race (OR = 1.35, 95% CI: 1.29–1.41), and being unmarried (OR = 1.17, 95% CI: 1.13–1.22) were associated with a distant stage at diagnosis. Higher tumor grade, younger age, and more recent year of diagnosis were also associated with distant-stage diagnosis. As a proxy for neighborhood context, the SDI can be used by cancer registries and related population-based studies to identify geographic areas that could be prioritized for cancer prevention and control efforts.
format	article
author	Oluwole Adeyemi Babatunde Whitney E. Zahnd Jan M. Eberth Andrew B. Lawson Swann Arp Adams Eric Adjei Boakye Melanie S. Jefferson Caitlin G. Allen John L. Pearce Hong Li Chanita Hughes Halbert
author_facet	Oluwole Adeyemi Babatunde Whitney E. Zahnd Jan M. Eberth Andrew B. Lawson Swann Arp Adams Eric Adjei Boakye Melanie S. Jefferson Caitlin G. Allen John L. Pearce Hong Li Chanita Hughes Halbert
author_sort	Oluwole Adeyemi Babatunde
title	Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina
title_short	Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina
title_full	Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina
title_fullStr	Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina
title_full_unstemmed	Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina
title_sort	association between neighborhood social deprivation and stage at diagnosis among breast cancer patients in south carolina
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/d09404301d0542c8b0fe01380c07bcc9
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Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina

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