A robot for high yield electrophysiology and morphology of single neurons in vivo

Single-cell characterization and perturbation of neurons is critical for revealing the structure-function relationship of brain cells. Here the authors develop a robot that performs single-cell electroporation and extracellular electrophysiology and can be used for performingin vivosingle-cell exper...

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Autores principales: Lu Li, Benjamin Ouellette, William A. Stoy, Emma J. Garren, Tanya L. Daigle, Craig R. Forest, Christof Koch, Hongkui Zeng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/d0946abd477b4cf0a15647001db28162
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Sumario:Single-cell characterization and perturbation of neurons is critical for revealing the structure-function relationship of brain cells. Here the authors develop a robot that performs single-cell electroporation and extracellular electrophysiology and can be used for performingin vivosingle-cell experiments in deep brain tissues optically difficult to access.