Highly modified and immunoactive N-glycans of the canine heartworm

The glycome of parasites can have immunomodulatory properties or help to avoid immune surveillance, but details are unknown. Here, Martini et al. characterize the N-glycome of the canine heartworm, reveal an unprecedented complexity, particularly in anionic N-glycans, and determine recognition by co...

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Autores principales:	Francesca Martini, Barbara Eckmair, Saša Štefanić, Chunsheng Jin, Monika Garg, Shi Yan, Carmen Jiménez-Castells, Alba Hykollari, Christine Neupert, Luigi Venco, Daniel Varón Silva, Iain B. H. Wilson, Katharina Paschinger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d0954d0dbc3147dca457458daafc0bb4
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spelling	oai:doaj.org-article:d0954d0dbc3147dca457458daafc0bb42021-12-02T15:35:40ZHighly modified and immunoactive N-glycans of the canine heartworm10.1038/s41467-018-07948-72041-1723https://doaj.org/article/d0954d0dbc3147dca457458daafc0bb42019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07948-7https://doaj.org/toc/2041-1723The glycome of parasites can have immunomodulatory properties or help to avoid immune surveillance, but details are unknown. Here, Martini et al. characterize the N-glycome of the canine heartworm, reveal an unprecedented complexity, particularly in anionic N-glycans, and determine recognition by components of the immune system.Francesca MartiniBarbara EckmairSaša ŠtefanićChunsheng JinMonika GargShi YanCarmen Jiménez-CastellsAlba HykollariChristine NeupertLuigi VencoDaniel Varón SilvaIain B. H. WilsonKatharina PaschingerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Francesca Martini Barbara Eckmair Saša Štefanić Chunsheng Jin Monika Garg Shi Yan Carmen Jiménez-Castells Alba Hykollari Christine Neupert Luigi Venco Daniel Varón Silva Iain B. H. Wilson Katharina Paschinger Highly modified and immunoactive N-glycans of the canine heartworm
description	The glycome of parasites can have immunomodulatory properties or help to avoid immune surveillance, but details are unknown. Here, Martini et al. characterize the N-glycome of the canine heartworm, reveal an unprecedented complexity, particularly in anionic N-glycans, and determine recognition by components of the immune system.
format	article
author	Francesca Martini Barbara Eckmair Saša Štefanić Chunsheng Jin Monika Garg Shi Yan Carmen Jiménez-Castells Alba Hykollari Christine Neupert Luigi Venco Daniel Varón Silva Iain B. H. Wilson Katharina Paschinger
author_facet	Francesca Martini Barbara Eckmair Saša Štefanić Chunsheng Jin Monika Garg Shi Yan Carmen Jiménez-Castells Alba Hykollari Christine Neupert Luigi Venco Daniel Varón Silva Iain B. H. Wilson Katharina Paschinger
author_sort	Francesca Martini
title	Highly modified and immunoactive N-glycans of the canine heartworm
title_short	Highly modified and immunoactive N-glycans of the canine heartworm
title_full	Highly modified and immunoactive N-glycans of the canine heartworm
title_fullStr	Highly modified and immunoactive N-glycans of the canine heartworm
title_full_unstemmed	Highly modified and immunoactive N-glycans of the canine heartworm
title_sort	highly modified and immunoactive n-glycans of the canine heartworm
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d0954d0dbc3147dca457458daafc0bb4
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Highly modified and immunoactive N-glycans of the canine heartworm

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