Thymodepressin—Unforeseen Immunosuppressor

The paper summarizes the available information concerning the biological properties and biomedical applications of Thymodepressin. This synthetic peptide drug displays pronounced immunoinhibitory activity across a wide range of conditions in vitro and in vivo. The history of its unforeseen discovery...

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Autores principales:	Vladislav I. Deigin, Julia E. Vinogradova, Dmitry L Vinogradov, Marina S. Krasilshchikova, Vadim T. Ivanov
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	new peptide immunosuppressor reciprocal activity peptide enantiomers autoimmune treatment comparison with cyclosporine A Organic chemistry QD241-441
Acceso en línea:	https://doaj.org/article/d09ad80eadc746f88de9644999e9ede6
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spelling	oai:doaj.org-article:d09ad80eadc746f88de9644999e9ede62021-11-11T18:32:03ZThymodepressin—Unforeseen Immunosuppressor10.3390/molecules262165501420-3049https://doaj.org/article/d09ad80eadc746f88de9644999e9ede62021-10-01T00:00:00Zhttps://www.mdpi.com/1420-3049/26/21/6550https://doaj.org/toc/1420-3049The paper summarizes the available information concerning the biological properties and biomedical applications of Thymodepressin. This synthetic peptide drug displays pronounced immunoinhibitory activity across a wide range of conditions in vitro and in vivo. The history of its unforeseen discovery is briefly reviewed, and the current as well as potential expansion areas of medicinal practice are outlined. Additional experimental evidence is obtained, demonstrating several potential advantages of Thymodepressin over another actively used immunosuppressor drug, cyclosporin A.Vladislav I. DeiginJulia E. VinogradovaDmitry L VinogradovMarina S. KrasilshchikovaVadim T. IvanovMDPI AGarticlenew peptide immunosuppressorreciprocal activity peptide enantiomersautoimmune treatmentcomparison with cyclosporine AOrganic chemistryQD241-441ENMolecules, Vol 26, Iss 6550, p 6550 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	new peptide immunosuppressor reciprocal activity peptide enantiomers autoimmune treatment comparison with cyclosporine A Organic chemistry QD241-441
spellingShingle	new peptide immunosuppressor reciprocal activity peptide enantiomers autoimmune treatment comparison with cyclosporine A Organic chemistry QD241-441 Vladislav I. Deigin Julia E. Vinogradova Dmitry L Vinogradov Marina S. Krasilshchikova Vadim T. Ivanov Thymodepressin—Unforeseen Immunosuppressor
description	The paper summarizes the available information concerning the biological properties and biomedical applications of Thymodepressin. This synthetic peptide drug displays pronounced immunoinhibitory activity across a wide range of conditions in vitro and in vivo. The history of its unforeseen discovery is briefly reviewed, and the current as well as potential expansion areas of medicinal practice are outlined. Additional experimental evidence is obtained, demonstrating several potential advantages of Thymodepressin over another actively used immunosuppressor drug, cyclosporin A.
format	article
author	Vladislav I. Deigin Julia E. Vinogradova Dmitry L Vinogradov Marina S. Krasilshchikova Vadim T. Ivanov
author_facet	Vladislav I. Deigin Julia E. Vinogradova Dmitry L Vinogradov Marina S. Krasilshchikova Vadim T. Ivanov
author_sort	Vladislav I. Deigin
title	Thymodepressin—Unforeseen Immunosuppressor
title_short	Thymodepressin—Unforeseen Immunosuppressor
title_full	Thymodepressin—Unforeseen Immunosuppressor
title_fullStr	Thymodepressin—Unforeseen Immunosuppressor
title_full_unstemmed	Thymodepressin—Unforeseen Immunosuppressor
title_sort	thymodepressin—unforeseen immunosuppressor
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/d09ad80eadc746f88de9644999e9ede6
work_keys_str_mv	AT vladislavideigin thymodepressinunforeseenimmunosuppressor AT juliaevinogradova thymodepressinunforeseenimmunosuppressor AT dmitrylvinogradov thymodepressinunforeseenimmunosuppressor AT marinaskrasilshchikova thymodepressinunforeseenimmunosuppressor AT vadimtivanov thymodepressinunforeseenimmunosuppressor
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Thymodepressin—Unforeseen Immunosuppressor

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