Inhibition of Classical and Alternative Modes of Respiration in <italic toggle="yes">Candida albicans</italic> Leads to Cell Wall Remodeling and Increased Macrophage Recognition

Inhibition of Classical and Alternative Modes of Respiration in <italic toggle="yes">Candida albicans</italic> Leads to Cell Wall Remodeling and Increased Macrophage Recognition

ABSTRACT The human fungal pathogen Candida albicans requires respiratory function for normal growth, morphogenesis, and virulence. Mitochondria therefore represent an enticing target for the development of new antifungal strategies. This possibility is bolstered by the presence of characteristics sp...

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Autores principales: Lucian Duvenage, Louise A. Walker, Aleksandra Bojarczuk, Simon A. Johnston, Donna M. MacCallum, Carol A. Munro, Campbell W. Gourlay
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
Candida albicans
cell wall
mitochondria
mycology
yeast
Microbiology
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Acceso en línea:https://doaj.org/article/d09b6a0106be494e92b07724b0b9b1ca
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