Novel Triterpenoids from <i>Cassia fistula</i> Stem Bark Depreciates STZ-Induced Detrimental Changes in IRS-1/Akt-Mediated Insulin Signaling Mechanisms in Type-1 Diabetic Rats

Here, we identified the mechanisms of action of antidiabetic activity of novel compounds isolated from <i>Cassia fistula</i> stem bark in STZ-diabetic animals. Novel triterpenoid compounds (C1, C2 and C3) were treated to STZ-administered diabetic animals at a concentration of 20mg/kg bod...

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Bibliographic Details
Main Authors: Sabapathy Indu, Periyasamy Vijayalakshmi, Jayaraman Selvaraj, Manikkam Rajalakshmi
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/d09cd8b953ad46df8f787b4aa0fdd6b9
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