Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas

Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas

Papillary thyroid cancer (PTC) is one of the most common type of endocrine malignancy. Here, the authors use proteogenomic approaches to analyse the primary tumour and lymph node metastases from a PTC patient and report an oncogenic RET fusion, and potential druggable targets from the ubiquitin sign...

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Autores principales: Aswini Krishnan, Jean Berthelet, Emilie Renaud, Sebastian Rosigkeit, Ute Distler, Eric Stawiski, Jing Wang, Zora Modrusan, Marc Fiedler, Mariann Bienz, Stefan Tenzer, Arno Schad, Wilfried Roth, Bernd Thiede, Somasekar Seshagiri, Thomas J. Musholt, Krishnaraj Rajalingam
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/d0a0473fc75243f2b229229426d6900d
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