Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis
Lipid induced stress contributes to metabolic diseases. Here the authors identify small nucleolar RNA 73 (SNORA73) in a screen for genes that protect against lipotoxicity and show that deficiency of SNORA73 reprograms oxidative metabolism and protects against steatohepatitis in mice.
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Auteurs principaux: | , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/d0b59c5a040d41be8c7d87c9047d2474 |
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