An integrative network-based approach for drug target indication expansion.
<h4>Background</h4>The identification of a target-indication pair is regarded as the first step in a traditional drug discovery and development process. Significant investment and attrition occur during discovery and development before a molecule is shown to be safe and efficacious for t...
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Autores principales: | Yingnan Han, Clarence Wang, Katherine Klinger, Deepak K Rajpal, Cheng Zhu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/d0c087013a1340469574ab1015671ef4 |
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