Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry

Tumor associated macrophages are functionally and phenotypically heterogeneous. Here the authors describe the spatial distribution of distinct macrophage populations within regions of gastric cancer and probe their associations with clinical outcomes, gene signatures and PDL1 expression.

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Autores principales:	Yu-Kuan Huang, Minyu Wang, Yu Sun, Natasha Di Costanzo, Catherine Mitchell, Adrian Achuthan, John A. Hamilton, Rita A. Busuttil, Alex Boussioutas
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d0c56775dacb4269a09a52b24c733fd5
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spelling	oai:doaj.org-article:d0c56775dacb4269a09a52b24c733fd52021-12-02T14:40:20ZMacrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry10.1038/s41467-019-11788-42041-1723https://doaj.org/article/d0c56775dacb4269a09a52b24c733fd52019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11788-4https://doaj.org/toc/2041-1723Tumor associated macrophages are functionally and phenotypically heterogeneous. Here the authors describe the spatial distribution of distinct macrophage populations within regions of gastric cancer and probe their associations with clinical outcomes, gene signatures and PDL1 expression.Yu-Kuan HuangMinyu WangYu SunNatasha Di CostanzoCatherine MitchellAdrian AchuthanJohn A. HamiltonRita A. BusuttilAlex BoussioutasNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yu-Kuan Huang Minyu Wang Yu Sun Natasha Di Costanzo Catherine Mitchell Adrian Achuthan John A. Hamilton Rita A. Busuttil Alex Boussioutas Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry
description	Tumor associated macrophages are functionally and phenotypically heterogeneous. Here the authors describe the spatial distribution of distinct macrophage populations within regions of gastric cancer and probe their associations with clinical outcomes, gene signatures and PDL1 expression.
format	article
author	Yu-Kuan Huang Minyu Wang Yu Sun Natasha Di Costanzo Catherine Mitchell Adrian Achuthan John A. Hamilton Rita A. Busuttil Alex Boussioutas
author_facet	Yu-Kuan Huang Minyu Wang Yu Sun Natasha Di Costanzo Catherine Mitchell Adrian Achuthan John A. Hamilton Rita A. Busuttil Alex Boussioutas
author_sort	Yu-Kuan Huang
title	Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry
title_short	Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry
title_full	Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry
title_fullStr	Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry
title_full_unstemmed	Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry
title_sort	macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d0c56775dacb4269a09a52b24c733fd5
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Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry

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