Immunoinformatics and Immunogenetics-Based Design of Immunogenic Peptides Vaccine against the Emerging Tick-Borne Encephalitis Virus (TBEV) and Its Validation through In Silico Cloning and Immune Simulation

Immunoinformatics and Immunogenetics-Based Design of Immunogenic Peptides Vaccine against the Emerging Tick-Borne Encephalitis Virus (TBEV) and Its Validation through In Silico Cloning and Immune Simulation

Pegivirus, HPgV, earlier known as Gb virus and hepatitis G virus, is an enveloped, positive-stranded RNA and lymphotropic virus classified into the Flaviviridae family. The transmission routes primarily involve blood products, with infections worldwide, leading up to 25% of persistent infections. To...

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Autores principales: Muhammad Suleman, Muhammad Tahir ul Qamar, Kiran, Samreen Rasool, Aneela Rasool, Aqel Albutti, Noorah Alsowayeh, Ameen S. S. Alwashmi, Mohammad Abdullah Aljasir, Sajjad Ahmad, Zahid Hussain, Muhammad Rizwan, Syed Shujait Ali, Abbas Khan, Dong-Qing Wei
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
Tick-borne encephalitis (TBE)
proteome mining
vaccine construct
in silico cloning
immune simulation
Medicine
R
Acceso en línea:https://doaj.org/article/d0c671d475e144ab999527a760bdbdef
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