Diagnostic challenges in epithelioid glioblastoma of the cerebellum: A case report

Epithelioid glioblastoma (eGB) is an uncommon morphological variant of isocitrate dehydrogenase wild-type GB that commonly presents as a cerebral mass in young adults and children. Here, we report the case of a 22-year-old man who presented with a cerebellar tumor. With the provisional diagnosis of...

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Autores principales: Phiza Aggarwal, Debajyoti Chatterjee, Vipin Kumar Gupta, Rekha Gupt
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Lenguaje:EN
Publicado: Wolters Kluwer Medknow Publications 2021
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Acceso en línea:https://doaj.org/article/d0d0de25ed9541fb9dd06a189c33bae7
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spelling oai:doaj.org-article:d0d0de25ed9541fb9dd06a189c33bae72021-11-19T10:42:03ZDiagnostic challenges in epithelioid glioblastoma of the cerebellum: A case report2589-61132589-612110.4103/glioma.glioma_13_21https://doaj.org/article/d0d0de25ed9541fb9dd06a189c33bae72021-01-01T00:00:00Zhttp://www.jglioma.com/article.asp?issn=2589-6113;year=2021;volume=4;issue=3;spage=54;epage=56;aulast=Aggarwalhttps://doaj.org/toc/2589-6113https://doaj.org/toc/2589-6121Epithelioid glioblastoma (eGB) is an uncommon morphological variant of isocitrate dehydrogenase wild-type GB that commonly presents as a cerebral mass in young adults and children. Here, we report the case of a 22-year-old man who presented with a cerebellar tumor. With the provisional diagnosis of pilocytic astrocytoma and adult medulloblastoma, he underwent suboccipital craniotomy with gross total excision of the tumor. On histopathological examination, he was diagnosed with eGB. Cerebellar presentation of eGB is a rare event that has not been previously described in the literature. The present case also highlights the need for differentiating eGB from its morphological mimics by carefully interpreting histopathological and immunohistochemical examination findings.Phiza AggarwalDebajyoti ChatterjeeVipin Kumar GuptaRekha GuptWolters Kluwer Medknow Publicationsarticleadult medulloblastomacase reportcerebellar tumorepithelioid cellsisocitrate dehydrogenase wild-type glioblastomapilocytic astrocytomaNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENGlioma, Vol 4, Iss 3, Pp 54-56 (2021)
institution DOAJ
collection DOAJ
language EN
topic adult medulloblastoma
case report
cerebellar tumor
epithelioid cells
isocitrate dehydrogenase wild-type glioblastoma
pilocytic astrocytoma
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
spellingShingle adult medulloblastoma
case report
cerebellar tumor
epithelioid cells
isocitrate dehydrogenase wild-type glioblastoma
pilocytic astrocytoma
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Phiza Aggarwal
Debajyoti Chatterjee
Vipin Kumar Gupta
Rekha Gupt
Diagnostic challenges in epithelioid glioblastoma of the cerebellum: A case report
description Epithelioid glioblastoma (eGB) is an uncommon morphological variant of isocitrate dehydrogenase wild-type GB that commonly presents as a cerebral mass in young adults and children. Here, we report the case of a 22-year-old man who presented with a cerebellar tumor. With the provisional diagnosis of pilocytic astrocytoma and adult medulloblastoma, he underwent suboccipital craniotomy with gross total excision of the tumor. On histopathological examination, he was diagnosed with eGB. Cerebellar presentation of eGB is a rare event that has not been previously described in the literature. The present case also highlights the need for differentiating eGB from its morphological mimics by carefully interpreting histopathological and immunohistochemical examination findings.
format article
author Phiza Aggarwal
Debajyoti Chatterjee
Vipin Kumar Gupta
Rekha Gupt
author_facet Phiza Aggarwal
Debajyoti Chatterjee
Vipin Kumar Gupta
Rekha Gupt
author_sort Phiza Aggarwal
title Diagnostic challenges in epithelioid glioblastoma of the cerebellum: A case report
title_short Diagnostic challenges in epithelioid glioblastoma of the cerebellum: A case report
title_full Diagnostic challenges in epithelioid glioblastoma of the cerebellum: A case report
title_fullStr Diagnostic challenges in epithelioid glioblastoma of the cerebellum: A case report
title_full_unstemmed Diagnostic challenges in epithelioid glioblastoma of the cerebellum: A case report
title_sort diagnostic challenges in epithelioid glioblastoma of the cerebellum: a case report
publisher Wolters Kluwer Medknow Publications
publishDate 2021
url https://doaj.org/article/d0d0de25ed9541fb9dd06a189c33bae7
work_keys_str_mv AT phizaaggarwal diagnosticchallengesinepithelioidglioblastomaofthecerebellumacasereport
AT debajyotichatterjee diagnosticchallengesinepithelioidglioblastomaofthecerebellumacasereport
AT vipinkumargupta diagnosticchallengesinepithelioidglioblastomaofthecerebellumacasereport
AT rekhagupt diagnosticchallengesinepithelioidglioblastomaofthecerebellumacasereport
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