Myxedema Coma and Acute Hepatopathy in a Dog with Severe Atherosclerosis

A 9-year-old male intact mixed-breed dog was presented to The Ohio State University Veterinary Medical Center for evaluation of two days’ duration of weakness, lethargy, inappetence, and one episode of vomiting the day of presentation. On presentation, the dog was depressed and tetraparetic. He was...

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Autores principales:	Leah C. Giralico, Rebecca Makii, Betsy A. Pray, Valerie J. Parker
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/d0d7eb3a3fd946a089bdc405adcdfc3d
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spelling	oai:doaj.org-article:d0d7eb3a3fd946a089bdc405adcdfc3d2021-11-08T02:36:32ZMyxedema Coma and Acute Hepatopathy in a Dog with Severe Atherosclerosis2090-701X10.1155/2021/6622767https://doaj.org/article/d0d7eb3a3fd946a089bdc405adcdfc3d2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/6622767https://doaj.org/toc/2090-701XA 9-year-old male intact mixed-breed dog was presented to The Ohio State University Veterinary Medical Center for evaluation of two days’ duration of weakness, lethargy, inappetence, and one episode of vomiting the day of presentation. On presentation, the dog was depressed and tetraparetic. He was noted to be icteric and dehydrated. Obesity and truncal alopecia with a “rat tail” appearance were observed. Diagnostic testing revealed evidence of an acute hepatopathy and peritonitis. Given the dog’s neurologic status, physical examination abnormalities, including a “tragic facial expression”, and hyperlipidemia, there was concern for possible myxedema coma. A thyroid panel was consistent with hypothyroidism. The dog experienced respiratory arrest prior to initiation of therapy, and an autopsy confirmed the presence of subacute necrotizing cholangiohepatitis, marked atherosclerosis, and severe thyroid atrophy. These clinical and pathologic changes were supportive of myxedema coma.Leah C. GiralicoRebecca MakiiBetsy A. PrayValerie J. ParkerHindawi LimitedarticleVeterinary medicineSF600-1100ENCase Reports in Veterinary Medicine, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Veterinary medicine SF600-1100
spellingShingle	Veterinary medicine SF600-1100 Leah C. Giralico Rebecca Makii Betsy A. Pray Valerie J. Parker Myxedema Coma and Acute Hepatopathy in a Dog with Severe Atherosclerosis
description	A 9-year-old male intact mixed-breed dog was presented to The Ohio State University Veterinary Medical Center for evaluation of two days’ duration of weakness, lethargy, inappetence, and one episode of vomiting the day of presentation. On presentation, the dog was depressed and tetraparetic. He was noted to be icteric and dehydrated. Obesity and truncal alopecia with a “rat tail” appearance were observed. Diagnostic testing revealed evidence of an acute hepatopathy and peritonitis. Given the dog’s neurologic status, physical examination abnormalities, including a “tragic facial expression”, and hyperlipidemia, there was concern for possible myxedema coma. A thyroid panel was consistent with hypothyroidism. The dog experienced respiratory arrest prior to initiation of therapy, and an autopsy confirmed the presence of subacute necrotizing cholangiohepatitis, marked atherosclerosis, and severe thyroid atrophy. These clinical and pathologic changes were supportive of myxedema coma.
format	article
author	Leah C. Giralico Rebecca Makii Betsy A. Pray Valerie J. Parker
author_facet	Leah C. Giralico Rebecca Makii Betsy A. Pray Valerie J. Parker
author_sort	Leah C. Giralico
title	Myxedema Coma and Acute Hepatopathy in a Dog with Severe Atherosclerosis
title_short	Myxedema Coma and Acute Hepatopathy in a Dog with Severe Atherosclerosis
title_full	Myxedema Coma and Acute Hepatopathy in a Dog with Severe Atherosclerosis
title_fullStr	Myxedema Coma and Acute Hepatopathy in a Dog with Severe Atherosclerosis
title_full_unstemmed	Myxedema Coma and Acute Hepatopathy in a Dog with Severe Atherosclerosis
title_sort	myxedema coma and acute hepatopathy in a dog with severe atherosclerosis
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/d0d7eb3a3fd946a089bdc405adcdfc3d
work_keys_str_mv	AT leahcgiralico myxedemacomaandacutehepatopathyinadogwithsevereatherosclerosis AT rebeccamakii myxedemacomaandacutehepatopathyinadogwithsevereatherosclerosis AT betsyapray myxedemacomaandacutehepatopathyinadogwithsevereatherosclerosis AT valeriejparker myxedemacomaandacutehepatopathyinadogwithsevereatherosclerosis
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Myxedema Coma and Acute Hepatopathy in a Dog with Severe Atherosclerosis

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