Prefrontal mechanisms combining rewards and beliefs in human decision-making

Optimal decision-making requires integrating expectations about rewards with beliefs about reward contingencies. Here, the authors show that these aspects of reward are encoded in the ventromedial prefrontal cortex then combined in the dorsomedial prefrontal cortex, a process that guides choice bias...

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Bibliographic Details
Main Authors: Marion Rouault, Jan Drugowitsch, Etienne Koechlin
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/d0f13d3f8e5144f792561710bb303c26
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Summary:Optimal decision-making requires integrating expectations about rewards with beliefs about reward contingencies. Here, the authors show that these aspects of reward are encoded in the ventromedial prefrontal cortex then combined in the dorsomedial prefrontal cortex, a process that guides choice biases characteristic of human decision-making.