Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection

Here, Ferren et al. isolate Syrian hamster brainstem and lung tissue to establish ex vivo culture systems to study SARS-CoV-2 local viral tropism, immune response and tissue pathology. Further, they provide evidence that these systems can be used for screening of anti-viral compounds.

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Autores principales:	Marion Ferren, Valérie Favède, Didier Decimo, Mathieu Iampietro, Nicole A. P. Lieberman, Jean-Luc Weickert, Rodolphe Pelissier, Magalie Mazelier, Olivier Terrier, Anne Moscona, Matteo Porotto, Alexander L. Greninger, Nadia Messaddeq, Branka Horvat, Cyrille Mathieu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d0f36ce0ff77494588238708b9573bc8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:d0f36ce0ff77494588238708b9573bc82021-12-02T19:16:20ZHamster organotypic modeling of SARS-CoV-2 lung and brainstem infection10.1038/s41467-021-26096-z2041-1723https://doaj.org/article/d0f36ce0ff77494588238708b9573bc82021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26096-zhttps://doaj.org/toc/2041-1723Here, Ferren et al. isolate Syrian hamster brainstem and lung tissue to establish ex vivo culture systems to study SARS-CoV-2 local viral tropism, immune response and tissue pathology. Further, they provide evidence that these systems can be used for screening of anti-viral compounds.Marion FerrenValérie FavèdeDidier DecimoMathieu IampietroNicole A. P. LiebermanJean-Luc WeickertRodolphe PelissierMagalie MazelierOlivier TerrierAnne MosconaMatteo PorottoAlexander L. GreningerNadia MessaddeqBranka HorvatCyrille MathieuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marion Ferren Valérie Favède Didier Decimo Mathieu Iampietro Nicole A. P. Lieberman Jean-Luc Weickert Rodolphe Pelissier Magalie Mazelier Olivier Terrier Anne Moscona Matteo Porotto Alexander L. Greninger Nadia Messaddeq Branka Horvat Cyrille Mathieu Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection
description	Here, Ferren et al. isolate Syrian hamster brainstem and lung tissue to establish ex vivo culture systems to study SARS-CoV-2 local viral tropism, immune response and tissue pathology. Further, they provide evidence that these systems can be used for screening of anti-viral compounds.
format	article
author	Marion Ferren Valérie Favède Didier Decimo Mathieu Iampietro Nicole A. P. Lieberman Jean-Luc Weickert Rodolphe Pelissier Magalie Mazelier Olivier Terrier Anne Moscona Matteo Porotto Alexander L. Greninger Nadia Messaddeq Branka Horvat Cyrille Mathieu
author_facet	Marion Ferren Valérie Favède Didier Decimo Mathieu Iampietro Nicole A. P. Lieberman Jean-Luc Weickert Rodolphe Pelissier Magalie Mazelier Olivier Terrier Anne Moscona Matteo Porotto Alexander L. Greninger Nadia Messaddeq Branka Horvat Cyrille Mathieu
author_sort	Marion Ferren
title	Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection
title_short	Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection
title_full	Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection
title_fullStr	Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection
title_full_unstemmed	Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection
title_sort	hamster organotypic modeling of sars-cov-2 lung and brainstem infection
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d0f36ce0ff77494588238708b9573bc8
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Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection

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