Clinical variability of the systemic juvenile idiopathic arthritis course: literature review based on case series

Systemic juvenile idiopathic arthritis (sJIA) is a heterogeneous category of arthritis that frequently leads to disability and severe complications. The clinical cause of sJIA is very variable, which results in difficulties of disease recognition. In this literature review based on case series we o...

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Autores principales:	Oksana Boyarchuk, Tetiana Kovalchuk, Nataliya Kovalchuk, Oksana Chubata
Formato:	article
Lenguaje:	EN
Publicado:	Termedia Publishing House 2020
Materias:	diagnosis macrophage activation syndrome systemic juvenile idiopathic arthritis. Medicine R
Acceso en línea:	https://doaj.org/article/d0f90f8bbf96420d93cda8b73038a459
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spelling	oai:doaj.org-article:d0f90f8bbf96420d93cda8b73038a4592021-12-02T19:19:13ZClinical variability of the systemic juvenile idiopathic arthritis course: literature review based on case series0034-62332084-983410.5114/reum.2020.102010https://doaj.org/article/d0f90f8bbf96420d93cda8b73038a4592020-12-01T00:00:00Zhttps://www.termedia.pl/Clinical-variability-of-the-systemic-juvenile-idiopathic-arthritis-course-literature-review-based-on-case-series,18,42778,1,1.htmlhttps://doaj.org/toc/0034-6233https://doaj.org/toc/2084-9834Systemic juvenile idiopathic arthritis (sJIA) is a heterogeneous category of arthritis that frequently leads to disability and severe complications. The clinical cause of sJIA is very variable, which results in difficulties of disease recognition. In this literature review based on case series we outline the main challenges in diagnostic of sJIA and macrophage activation syndrome (MAS). Using the 2016 criteria for MAS diagnostic allowed to consider MAS in the diagnostically challenging cases, that confirms their sensitivity in pediatric patients. The reviewed literature showed last updates for the improvement of classification, diagnostic of sJIA and its complication. The modification of JIA criteria, initiated by Paediatric Rheumatology International Trials Organisation, will allow to improve detection and treatment of JIA. The presentation of this clinical cases and the discussion may be useful for understanding the disease cause and will help to differentiate sJIA and MAS from other disorders, and to improve treatment outcomes.Oksana BoyarchukTetiana KovalchukNataliya KovalchukOksana ChubataTermedia Publishing Housearticlediagnosis macrophage activation syndrome systemic juvenile idiopathic arthritis.MedicineRENRheumatology, Vol 58, Iss 6, Pp 436-443 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	diagnosis macrophage activation syndrome systemic juvenile idiopathic arthritis. Medicine R
spellingShingle	diagnosis macrophage activation syndrome systemic juvenile idiopathic arthritis. Medicine R Oksana Boyarchuk Tetiana Kovalchuk Nataliya Kovalchuk Oksana Chubata Clinical variability of the systemic juvenile idiopathic arthritis course: literature review based on case series
description	Systemic juvenile idiopathic arthritis (sJIA) is a heterogeneous category of arthritis that frequently leads to disability and severe complications. The clinical cause of sJIA is very variable, which results in difficulties of disease recognition. In this literature review based on case series we outline the main challenges in diagnostic of sJIA and macrophage activation syndrome (MAS). Using the 2016 criteria for MAS diagnostic allowed to consider MAS in the diagnostically challenging cases, that confirms their sensitivity in pediatric patients. The reviewed literature showed last updates for the improvement of classification, diagnostic of sJIA and its complication. The modification of JIA criteria, initiated by Paediatric Rheumatology International Trials Organisation, will allow to improve detection and treatment of JIA. The presentation of this clinical cases and the discussion may be useful for understanding the disease cause and will help to differentiate sJIA and MAS from other disorders, and to improve treatment outcomes.
format	article
author	Oksana Boyarchuk Tetiana Kovalchuk Nataliya Kovalchuk Oksana Chubata
author_facet	Oksana Boyarchuk Tetiana Kovalchuk Nataliya Kovalchuk Oksana Chubata
author_sort	Oksana Boyarchuk
title	Clinical variability of the systemic juvenile idiopathic arthritis course: literature review based on case series
title_short	Clinical variability of the systemic juvenile idiopathic arthritis course: literature review based on case series
title_full	Clinical variability of the systemic juvenile idiopathic arthritis course: literature review based on case series
title_fullStr	Clinical variability of the systemic juvenile idiopathic arthritis course: literature review based on case series
title_full_unstemmed	Clinical variability of the systemic juvenile idiopathic arthritis course: literature review based on case series
title_sort	clinical variability of the systemic juvenile idiopathic arthritis course: literature review based on case series
publisher	Termedia Publishing House
publishDate	2020
url	https://doaj.org/article/d0f90f8bbf96420d93cda8b73038a459
work_keys_str_mv	AT oksanaboyarchuk clinicalvariabilityofthesystemicjuvenileidiopathicarthritiscourseliteraturereviewbasedoncaseseries AT tetianakovalchuk clinicalvariabilityofthesystemicjuvenileidiopathicarthritiscourseliteraturereviewbasedoncaseseries AT nataliyakovalchuk clinicalvariabilityofthesystemicjuvenileidiopathicarthritiscourseliteraturereviewbasedoncaseseries AT oksanachubata clinicalvariabilityofthesystemicjuvenileidiopathicarthritiscourseliteraturereviewbasedoncaseseries
_version_	1718376881480269824

Clinical variability of the systemic juvenile idiopathic arthritis course: literature review based on case series

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