Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model

How embryonic melanoblast behaviour influences adult pigmentation patterns and causes patterning defects is unclear. Here, Mort et al. construct a stochastic model parameterised experimentally to show that melanoblast migration is undirected and that reduced proliferation causes patterning defects.

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Autores principales: Richard L. Mort, Robert J. H. Ross, Kirsten J. Hainey, Olivia J. Harrison, Margaret A. Keighren, Gabriel Landini, Ruth E. Baker, Kevin J. Painter, Ian J. Jackson, Christian A. Yates
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/d0fc4d265c144b5a892537bce05adc94
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spelling oai:doaj.org-article:d0fc4d265c144b5a892537bce05adc942021-12-02T17:32:51ZReconciling diverse mammalian pigmentation patterns with a fundamental mathematical model10.1038/ncomms102882041-1723https://doaj.org/article/d0fc4d265c144b5a892537bce05adc942016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10288https://doaj.org/toc/2041-1723How embryonic melanoblast behaviour influences adult pigmentation patterns and causes patterning defects is unclear. Here, Mort et al. construct a stochastic model parameterised experimentally to show that melanoblast migration is undirected and that reduced proliferation causes patterning defects.Richard L. MortRobert J. H. RossKirsten J. HaineyOlivia J. HarrisonMargaret A. KeighrenGabriel LandiniRuth E. BakerKevin J. PainterIan J. JacksonChristian A. YatesNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Richard L. Mort
Robert J. H. Ross
Kirsten J. Hainey
Olivia J. Harrison
Margaret A. Keighren
Gabriel Landini
Ruth E. Baker
Kevin J. Painter
Ian J. Jackson
Christian A. Yates
Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model
description How embryonic melanoblast behaviour influences adult pigmentation patterns and causes patterning defects is unclear. Here, Mort et al. construct a stochastic model parameterised experimentally to show that melanoblast migration is undirected and that reduced proliferation causes patterning defects.
format article
author Richard L. Mort
Robert J. H. Ross
Kirsten J. Hainey
Olivia J. Harrison
Margaret A. Keighren
Gabriel Landini
Ruth E. Baker
Kevin J. Painter
Ian J. Jackson
Christian A. Yates
author_facet Richard L. Mort
Robert J. H. Ross
Kirsten J. Hainey
Olivia J. Harrison
Margaret A. Keighren
Gabriel Landini
Ruth E. Baker
Kevin J. Painter
Ian J. Jackson
Christian A. Yates
author_sort Richard L. Mort
title Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model
title_short Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model
title_full Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model
title_fullStr Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model
title_full_unstemmed Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model
title_sort reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/d0fc4d265c144b5a892537bce05adc94
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