Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model
How embryonic melanoblast behaviour influences adult pigmentation patterns and causes patterning defects is unclear. Here, Mort et al. construct a stochastic model parameterised experimentally to show that melanoblast migration is undirected and that reduced proliferation causes patterning defects.
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Nature Portfolio
2016
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oai:doaj.org-article:d0fc4d265c144b5a892537bce05adc942021-12-02T17:32:51ZReconciling diverse mammalian pigmentation patterns with a fundamental mathematical model10.1038/ncomms102882041-1723https://doaj.org/article/d0fc4d265c144b5a892537bce05adc942016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10288https://doaj.org/toc/2041-1723How embryonic melanoblast behaviour influences adult pigmentation patterns and causes patterning defects is unclear. Here, Mort et al. construct a stochastic model parameterised experimentally to show that melanoblast migration is undirected and that reduced proliferation causes patterning defects.Richard L. MortRobert J. H. RossKirsten J. HaineyOlivia J. HarrisonMargaret A. KeighrenGabriel LandiniRuth E. BakerKevin J. PainterIan J. JacksonChristian A. YatesNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
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Science Q Richard L. Mort Robert J. H. Ross Kirsten J. Hainey Olivia J. Harrison Margaret A. Keighren Gabriel Landini Ruth E. Baker Kevin J. Painter Ian J. Jackson Christian A. Yates Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model |
description |
How embryonic melanoblast behaviour influences adult pigmentation patterns and causes patterning defects is unclear. Here, Mort et al. construct a stochastic model parameterised experimentally to show that melanoblast migration is undirected and that reduced proliferation causes patterning defects. |
format |
article |
author |
Richard L. Mort Robert J. H. Ross Kirsten J. Hainey Olivia J. Harrison Margaret A. Keighren Gabriel Landini Ruth E. Baker Kevin J. Painter Ian J. Jackson Christian A. Yates |
author_facet |
Richard L. Mort Robert J. H. Ross Kirsten J. Hainey Olivia J. Harrison Margaret A. Keighren Gabriel Landini Ruth E. Baker Kevin J. Painter Ian J. Jackson Christian A. Yates |
author_sort |
Richard L. Mort |
title |
Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model |
title_short |
Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model |
title_full |
Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model |
title_fullStr |
Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model |
title_full_unstemmed |
Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model |
title_sort |
reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/d0fc4d265c144b5a892537bce05adc94 |
work_keys_str_mv |
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