Non-competitive resource exploitation within mosquito shapes within-host malaria infectivity and virulence

The evolution of within-host malaria virulence has been studied, but the vector’s contribution isn’t well understood. Here, Costa et al. show that non-competitive parasitic resource exploitation within-vector, in particular lipid trafficking, restricts within-host infectivity and virulence of the pa...

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Autores principales:	G. Costa, M. Gildenhard, M. Eldering, R. L. Lindquist, A. E. Hauser, R. Sauerwein, C. Goosmann, V. Brinkmann, P. Carrillo-Bustamante, E. A. Levashina
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d0ff37703f7c4f89aa8c57e9682c2d38
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spelling	oai:doaj.org-article:d0ff37703f7c4f89aa8c57e9682c2d382021-12-02T17:31:14ZNon-competitive resource exploitation within mosquito shapes within-host malaria infectivity and virulence10.1038/s41467-018-05893-z2041-1723https://doaj.org/article/d0ff37703f7c4f89aa8c57e9682c2d382018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05893-zhttps://doaj.org/toc/2041-1723The evolution of within-host malaria virulence has been studied, but the vector’s contribution isn’t well understood. Here, Costa et al. show that non-competitive parasitic resource exploitation within-vector, in particular lipid trafficking, restricts within-host infectivity and virulence of the parasite.G. CostaM. GildenhardM. ElderingR. L. LindquistA. E. HauserR. SauerweinC. GoosmannV. BrinkmannP. Carrillo-BustamanteE. A. LevashinaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q G. Costa M. Gildenhard M. Eldering R. L. Lindquist A. E. Hauser R. Sauerwein C. Goosmann V. Brinkmann P. Carrillo-Bustamante E. A. Levashina Non-competitive resource exploitation within mosquito shapes within-host malaria infectivity and virulence
description	The evolution of within-host malaria virulence has been studied, but the vector’s contribution isn’t well understood. Here, Costa et al. show that non-competitive parasitic resource exploitation within-vector, in particular lipid trafficking, restricts within-host infectivity and virulence of the parasite.
format	article
author	G. Costa M. Gildenhard M. Eldering R. L. Lindquist A. E. Hauser R. Sauerwein C. Goosmann V. Brinkmann P. Carrillo-Bustamante E. A. Levashina
author_facet	G. Costa M. Gildenhard M. Eldering R. L. Lindquist A. E. Hauser R. Sauerwein C. Goosmann V. Brinkmann P. Carrillo-Bustamante E. A. Levashina
author_sort	G. Costa
title	Non-competitive resource exploitation within mosquito shapes within-host malaria infectivity and virulence
title_short	Non-competitive resource exploitation within mosquito shapes within-host malaria infectivity and virulence
title_full	Non-competitive resource exploitation within mosquito shapes within-host malaria infectivity and virulence
title_fullStr	Non-competitive resource exploitation within mosquito shapes within-host malaria infectivity and virulence
title_full_unstemmed	Non-competitive resource exploitation within mosquito shapes within-host malaria infectivity and virulence
title_sort	non-competitive resource exploitation within mosquito shapes within-host malaria infectivity and virulence
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/d0ff37703f7c4f89aa8c57e9682c2d38
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Non-competitive resource exploitation within mosquito shapes within-host malaria infectivity and virulence

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