Intratumoral CXCR5+CD8+T associates with favorable clinical outcomes and immunogenic contexture in gastric cancer

Intratumoral CXCR5+CD8+T associates with favorable clinical outcomes and immunogenic contexture in gastric cancer

The prognostic value of tumor infiltrating lymphocytes in gastric cancer remains controversial. Here the authors show a consistent association between higher density of intratumoral CXCR5+CD8+ T cells and longer overall survival in four different cohorts of patients with gastric cancer.

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Autores principales: Jieti Wang, Ruochen Li, Yifan Cao, Yun Gu, Hanji Fang, Yuchao Fei, Kunpeng Lv, Xudong He, Chao Lin, Hao Liu, Heng Zhang, He Li, Hongyong He, Jiejie Xu, Hua Huang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d1117833dc914833b9186d17c51c3a9f
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spelling oai:doaj.org-article:d1117833dc914833b9186d17c51c3a9f2021-12-02T16:52:57ZIntratumoral CXCR5+CD8+T associates with favorable clinical outcomes and immunogenic contexture in gastric cancer10.1038/s41467-021-23356-w2041-1723https://doaj.org/article/d1117833dc914833b9186d17c51c3a9f2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23356-whttps://doaj.org/toc/2041-1723The prognostic value of tumor infiltrating lymphocytes in gastric cancer remains controversial. Here the authors show a consistent association between higher density of intratumoral CXCR5+CD8+ T cells and longer overall survival in four different cohorts of patients with gastric cancer.Jieti WangRuochen LiYifan CaoYun GuHanji FangYuchao FeiKunpeng LvXudong HeChao LinHao LiuHeng ZhangHe LiHongyong HeJiejie XuHua HuangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jieti Wang
Ruochen Li
Yifan Cao
Yun Gu
Hanji Fang
Yuchao Fei
Kunpeng Lv
Xudong He
Chao Lin
Hao Liu
Heng Zhang
He Li
Hongyong He
Jiejie Xu
Hua Huang
Intratumoral CXCR5+CD8+T associates with favorable clinical outcomes and immunogenic contexture in gastric cancer
description The prognostic value of tumor infiltrating lymphocytes in gastric cancer remains controversial. Here the authors show a consistent association between higher density of intratumoral CXCR5+CD8+ T cells and longer overall survival in four different cohorts of patients with gastric cancer.
format article
author Jieti Wang
Ruochen Li
Yifan Cao
Yun Gu
Hanji Fang
Yuchao Fei
Kunpeng Lv
Xudong He
Chao Lin
Hao Liu
Heng Zhang
He Li
Hongyong He
Jiejie Xu
Hua Huang
author_facet Jieti Wang
Ruochen Li
Yifan Cao
Yun Gu
Hanji Fang
Yuchao Fei
Kunpeng Lv
Xudong He
Chao Lin
Hao Liu
Heng Zhang
He Li
Hongyong He
Jiejie Xu
Hua Huang
author_sort Jieti Wang
title Intratumoral CXCR5+CD8+T associates with favorable clinical outcomes and immunogenic contexture in gastric cancer
title_short Intratumoral CXCR5+CD8+T associates with favorable clinical outcomes and immunogenic contexture in gastric cancer
title_full Intratumoral CXCR5+CD8+T associates with favorable clinical outcomes and immunogenic contexture in gastric cancer
title_fullStr Intratumoral CXCR5+CD8+T associates with favorable clinical outcomes and immunogenic contexture in gastric cancer
title_full_unstemmed Intratumoral CXCR5+CD8+T associates with favorable clinical outcomes and immunogenic contexture in gastric cancer
title_sort intratumoral cxcr5+cd8+t associates with favorable clinical outcomes and immunogenic contexture in gastric cancer
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/d1117833dc914833b9186d17c51c3a9f
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