Protein deubiquitylase USP3 stabilizes Aurora A to promote proliferation and metastasis of esophageal squamous cell carcinoma

Abstract Aurora A kinase is a cell cycle regulator that is dysregulated in several different malignancies. Nevertheless, its regulatory mechanisms are still not fully understood. Here, we report that ubiquitin specific peptidase 3 (USP3) promotes proliferation and metastasis of esophageal squamous c...

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Autores principales: Ke Shi, Jin Zhong Zhang, Liang Yang, Ning-Ning Li, Ying Yue, Xiu-Hong Du, Xiu-Zhi Zhang, Yu Cheng Lu, Dan Guo
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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EMT
Acceso en línea:https://doaj.org/article/d1128292aea34b7d89e20b01b1e11941
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