Temperature-dependent growth of Geomyces destructans, the fungus that causes bat white-nose syndrome.

White-nose syndrome (WNS) is an emergent disease estimated to have killed over five million North American bats. Caused by the psychrophilic fungus Geomyces destructans, WNS specifically affects bats during hibernation. We describe temperature-dependent growth performance and morphology for six inde...

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Autores principales:	Michelle L Verant, Justin G Boyles, William Waldrep, Gudrun Wibbelt, David S Blehert
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d115b7c2a828400cb7bbd8868cb66585
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spelling	oai:doaj.org-article:d115b7c2a828400cb7bbd8868cb665852021-11-18T08:13:42ZTemperature-dependent growth of Geomyces destructans, the fungus that causes bat white-nose syndrome.1932-620310.1371/journal.pone.0046280https://doaj.org/article/d115b7c2a828400cb7bbd8868cb665852012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23029462/?tool=EBIhttps://doaj.org/toc/1932-6203White-nose syndrome (WNS) is an emergent disease estimated to have killed over five million North American bats. Caused by the psychrophilic fungus Geomyces destructans, WNS specifically affects bats during hibernation. We describe temperature-dependent growth performance and morphology for six independent isolates of G. destructans from North America and Europe. Thermal performance curves for all isolates displayed an intermediate peak with rapid decline in performance above the peak. Optimal temperatures for growth were between 12.5 and 15.8°C, and the upper critical temperature for growth was between 19.0 and 19.8°C. Growth rates varied across isolates, irrespective of geographic origin, and above 12°C all isolates displayed atypical morphology that may have implications for proliferation of the fungus. This study demonstrates that small variations in temperature, consistent with those inherent of bat hibernacula, affect growth performance and physiology of G. destructans, which may influence temperature-dependent progression and severity of WNS in wild bats.Michelle L VerantJustin G BoylesWilliam WaldrepGudrun WibbeltDavid S BlehertPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 9, p e46280 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Michelle L Verant Justin G Boyles William Waldrep Gudrun Wibbelt David S Blehert Temperature-dependent growth of Geomyces destructans, the fungus that causes bat white-nose syndrome.
description	White-nose syndrome (WNS) is an emergent disease estimated to have killed over five million North American bats. Caused by the psychrophilic fungus Geomyces destructans, WNS specifically affects bats during hibernation. We describe temperature-dependent growth performance and morphology for six independent isolates of G. destructans from North America and Europe. Thermal performance curves for all isolates displayed an intermediate peak with rapid decline in performance above the peak. Optimal temperatures for growth were between 12.5 and 15.8°C, and the upper critical temperature for growth was between 19.0 and 19.8°C. Growth rates varied across isolates, irrespective of geographic origin, and above 12°C all isolates displayed atypical morphology that may have implications for proliferation of the fungus. This study demonstrates that small variations in temperature, consistent with those inherent of bat hibernacula, affect growth performance and physiology of G. destructans, which may influence temperature-dependent progression and severity of WNS in wild bats.
format	article
author	Michelle L Verant Justin G Boyles William Waldrep Gudrun Wibbelt David S Blehert
author_facet	Michelle L Verant Justin G Boyles William Waldrep Gudrun Wibbelt David S Blehert
author_sort	Michelle L Verant
title	Temperature-dependent growth of Geomyces destructans, the fungus that causes bat white-nose syndrome.
title_short	Temperature-dependent growth of Geomyces destructans, the fungus that causes bat white-nose syndrome.
title_full	Temperature-dependent growth of Geomyces destructans, the fungus that causes bat white-nose syndrome.
title_fullStr	Temperature-dependent growth of Geomyces destructans, the fungus that causes bat white-nose syndrome.
title_full_unstemmed	Temperature-dependent growth of Geomyces destructans, the fungus that causes bat white-nose syndrome.
title_sort	temperature-dependent growth of geomyces destructans, the fungus that causes bat white-nose syndrome.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/d115b7c2a828400cb7bbd8868cb66585
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Temperature-dependent growth of Geomyces destructans, the fungus that causes bat white-nose syndrome.

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