Heteroresistance to Fluconazole Is a Continuously Distributed Phenotype among <named-content content-type="genus-species">Candida glabrata</named-content> Clinical Strains Associated with <italic toggle="yes">In Vivo</italic> Persistence

ABSTRACT Candida glabrata causes persistent infections in patients treated with fluconazole and often acquires resistance following exposure to the drug. Here we found that clinical strains of C. glabrata exhibit cell-to-cell variation in drug response (heteroresistance). We used population analysis...

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Autores principales: Ronen Ben-Ami, Offer Zimmerman, Talya Finn, Sharon Amit, Anna Novikov, Noa Wertheimer, Mor Lurie-Weinberger, Judith Berman
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
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Acceso en línea:https://doaj.org/article/d11681c6648a4cfe94be9a524d353a87
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