Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin

Endophilins-A are conserved membrane-associated proteins required for endocytosis. Here, the authors report that endophilins-A also promote exocytosis of neurosecretory vesicles by coordinating priming and fusion through intersectin-1, independently of their roles in different types of endocytosis.

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Autores principales:	Sindhuja Gowrisankaran, Sébastien Houy, Johanna G. Peña del Castillo, Vicky Steubler, Monika Gelker, Jana Kroll, Paulo S. Pinheiro, Dirk Schwitters, Nils Halbsgut, Arndt Pechstein, Jan R. T. van Weering, Tanja Maritzen, Volker Haucke, Nuno Raimundo, Jakob B. Sørensen, Ira Milosevic
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d12b951e45ac43b1b8a71db762ee3203
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spelling	oai:doaj.org-article:d12b951e45ac43b1b8a71db762ee32032021-12-02T15:39:26ZEndophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin10.1038/s41467-020-14993-82041-1723https://doaj.org/article/d12b951e45ac43b1b8a71db762ee32032020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14993-8https://doaj.org/toc/2041-1723Endophilins-A are conserved membrane-associated proteins required for endocytosis. Here, the authors report that endophilins-A also promote exocytosis of neurosecretory vesicles by coordinating priming and fusion through intersectin-1, independently of their roles in different types of endocytosis.Sindhuja GowrisankaranSébastien HouyJohanna G. Peña del CastilloVicky SteublerMonika GelkerJana KrollPaulo S. PinheiroDirk SchwittersNils HalbsgutArndt PechsteinJan R. T. van WeeringTanja MaritzenVolker HauckeNuno RaimundoJakob B. SørensenIra MilosevicNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sindhuja Gowrisankaran Sébastien Houy Johanna G. Peña del Castillo Vicky Steubler Monika Gelker Jana Kroll Paulo S. Pinheiro Dirk Schwitters Nils Halbsgut Arndt Pechstein Jan R. T. van Weering Tanja Maritzen Volker Haucke Nuno Raimundo Jakob B. Sørensen Ira Milosevic Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin
description	Endophilins-A are conserved membrane-associated proteins required for endocytosis. Here, the authors report that endophilins-A also promote exocytosis of neurosecretory vesicles by coordinating priming and fusion through intersectin-1, independently of their roles in different types of endocytosis.
format	article
author	Sindhuja Gowrisankaran Sébastien Houy Johanna G. Peña del Castillo Vicky Steubler Monika Gelker Jana Kroll Paulo S. Pinheiro Dirk Schwitters Nils Halbsgut Arndt Pechstein Jan R. T. van Weering Tanja Maritzen Volker Haucke Nuno Raimundo Jakob B. Sørensen Ira Milosevic
author_facet	Sindhuja Gowrisankaran Sébastien Houy Johanna G. Peña del Castillo Vicky Steubler Monika Gelker Jana Kroll Paulo S. Pinheiro Dirk Schwitters Nils Halbsgut Arndt Pechstein Jan R. T. van Weering Tanja Maritzen Volker Haucke Nuno Raimundo Jakob B. Sørensen Ira Milosevic
author_sort	Sindhuja Gowrisankaran
title	Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin
title_short	Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin
title_full	Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin
title_fullStr	Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin
title_full_unstemmed	Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin
title_sort	endophilin-a coordinates priming and fusion of neurosecretory vesicles via intersectin
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/d12b951e45ac43b1b8a71db762ee3203
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Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin

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