Retinal transplantation of photoreceptors results in donor–host cytoplasmic exchange

Integration of transplanted photoreceptors into the host retina has been assumed as the underlying mechanism for vision improvement in pre-clinical studies. Here, the authors show that the majority of transplanted photoreceptors do not structurally integrate but exchange intercellular material with...

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Autores principales:	Tiago Santos-Ferreira, Sílvia Llonch, Oliver Borsch, Kai Postel, Jochen Haas, Marius Ader
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d130eae8679243cab91029177e74c7b8
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spelling	oai:doaj.org-article:d130eae8679243cab91029177e74c7b82021-12-02T17:31:52ZRetinal transplantation of photoreceptors results in donor–host cytoplasmic exchange10.1038/ncomms130282041-1723https://doaj.org/article/d130eae8679243cab91029177e74c7b82016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13028https://doaj.org/toc/2041-1723Integration of transplanted photoreceptors into the host retina has been assumed as the underlying mechanism for vision improvement in pre-clinical studies. Here, the authors show that the majority of transplanted photoreceptors do not structurally integrate but exchange intercellular material with host cells.Tiago Santos-FerreiraSílvia LlonchOliver BorschKai PostelJochen HaasMarius AderNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tiago Santos-Ferreira Sílvia Llonch Oliver Borsch Kai Postel Jochen Haas Marius Ader Retinal transplantation of photoreceptors results in donor–host cytoplasmic exchange
description	Integration of transplanted photoreceptors into the host retina has been assumed as the underlying mechanism for vision improvement in pre-clinical studies. Here, the authors show that the majority of transplanted photoreceptors do not structurally integrate but exchange intercellular material with host cells.
format	article
author	Tiago Santos-Ferreira Sílvia Llonch Oliver Borsch Kai Postel Jochen Haas Marius Ader
author_facet	Tiago Santos-Ferreira Sílvia Llonch Oliver Borsch Kai Postel Jochen Haas Marius Ader
author_sort	Tiago Santos-Ferreira
title	Retinal transplantation of photoreceptors results in donor–host cytoplasmic exchange
title_short	Retinal transplantation of photoreceptors results in donor–host cytoplasmic exchange
title_full	Retinal transplantation of photoreceptors results in donor–host cytoplasmic exchange
title_fullStr	Retinal transplantation of photoreceptors results in donor–host cytoplasmic exchange
title_full_unstemmed	Retinal transplantation of photoreceptors results in donor–host cytoplasmic exchange
title_sort	retinal transplantation of photoreceptors results in donor–host cytoplasmic exchange
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/d130eae8679243cab91029177e74c7b8
work_keys_str_mv	AT tiagosantosferreira retinaltransplantationofphotoreceptorsresultsindonorhostcytoplasmicexchange AT silviallonch retinaltransplantationofphotoreceptorsresultsindonorhostcytoplasmicexchange AT oliverborsch retinaltransplantationofphotoreceptorsresultsindonorhostcytoplasmicexchange AT kaipostel retinaltransplantationofphotoreceptorsresultsindonorhostcytoplasmicexchange AT jochenhaas retinaltransplantationofphotoreceptorsresultsindonorhostcytoplasmicexchange AT mariusader retinaltransplantationofphotoreceptorsresultsindonorhostcytoplasmicexchange
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Retinal transplantation of photoreceptors results in donor–host cytoplasmic exchange

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