The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation

The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation

Visceral and subcutaneous fat are associated with different metabolic risk, but mediators of such depot specific effects are not very well known. Here the authors identify the transcriptional regulator, TRIP-Br2, as a regulator of endoplasmic reticulum (ER) stress-induced inflammatory responses spec...

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Autores principales: Guifen Qiang, Hyerim Whang Kong, Difeng Fang, Maximilian McCann, Xiuying Yang, Guanhua Du, Matthias Blüher, Jinfang Zhu, Chong Wee Liew
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/d145f4d2d68b4d5c8afc9fb6d1e6e4a0
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spelling oai:doaj.org-article:d145f4d2d68b4d5c8afc9fb6d1e6e4a02021-12-02T14:40:11ZThe obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation10.1038/ncomms113782041-1723https://doaj.org/article/d145f4d2d68b4d5c8afc9fb6d1e6e4a02016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11378https://doaj.org/toc/2041-1723Visceral and subcutaneous fat are associated with different metabolic risk, but mediators of such depot specific effects are not very well known. Here the authors identify the transcriptional regulator, TRIP-Br2, as a regulator of endoplasmic reticulum (ER) stress-induced inflammatory responses specifically in visceral fat.Guifen QiangHyerim Whang KongDifeng FangMaximilian McCannXiuying YangGuanhua DuMatthias BlüherJinfang ZhuChong Wee LiewNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Guifen Qiang
Hyerim Whang Kong
Difeng Fang
Maximilian McCann
Xiuying Yang
Guanhua Du
Matthias Blüher
Jinfang Zhu
Chong Wee Liew
The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation
description Visceral and subcutaneous fat are associated with different metabolic risk, but mediators of such depot specific effects are not very well known. Here the authors identify the transcriptional regulator, TRIP-Br2, as a regulator of endoplasmic reticulum (ER) stress-induced inflammatory responses specifically in visceral fat.
format article
author Guifen Qiang
Hyerim Whang Kong
Difeng Fang
Maximilian McCann
Xiuying Yang
Guanhua Du
Matthias Blüher
Jinfang Zhu
Chong Wee Liew
author_facet Guifen Qiang
Hyerim Whang Kong
Difeng Fang
Maximilian McCann
Xiuying Yang
Guanhua Du
Matthias Blüher
Jinfang Zhu
Chong Wee Liew
author_sort Guifen Qiang
title The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation
title_short The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation
title_full The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation
title_fullStr The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation
title_full_unstemmed The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation
title_sort obesity-induced transcriptional regulator trip-br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/d145f4d2d68b4d5c8afc9fb6d1e6e4a0
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