Helicobacter pylori infection in Chinese patients with atrial fibrillation

De-Zhao Wang,1 Wei Chen,1 Song Yang,2 Jun Wang,3 Qun Li,1 Qiang Fu,2 Shi-Jing Li,3 Bu-Xing Chen1 1Department of Cardiology, Beijing Tiantan Hospital, Capital Medical University, 2Department of Ultrasonography, Beijing Tiantan Hospital, Capital Medical University, 3Department of Cardiology, Beijing...

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Autores principales:	Wang DZ, Chen W, Yang S, Wang J, Li Q, Fu Q, Li SJ, Chen BX
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Helicobacter pylori high sensitivity C-reactive protein left atrial diameter atrial fibrillation 13C urea breath test. Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/d14613f66c6d4466b7131c0f2a567011
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spelling	oai:doaj.org-article:d14613f66c6d4466b7131c0f2a5670112021-12-02T00:16:51ZHelicobacter pylori infection in Chinese patients with atrial fibrillation1178-1998https://doaj.org/article/d14613f66c6d4466b7131c0f2a5670112015-04-01T00:00:00Zhttps://www.dovepress.com/helicobacter-pylori-infection-in-chinese-patients-with-atrial-fibrilla-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998De-Zhao Wang,1 Wei Chen,1 Song Yang,2 Jun Wang,3 Qun Li,1 Qiang Fu,2 Shi-Jing Li,3 Bu-Xing Chen1 1Department of Cardiology, Beijing Tiantan Hospital, Capital Medical University, 2Department of Ultrasonography, Beijing Tiantan Hospital, Capital Medical University, 3Department of Cardiology, Beijing Mentougou District Hospital, Beijing, People’s Republic of China Objective: To explore the relationship between Helicobacter pylori (Hp) infection and atrial fibrillation (AF) in Chinese patients.Methods: A total of 285 hospitalized patients with AF and 300 patients from Health Screening Center who matched age and sex with AF group were enrolled. AF patients were divided into two groups: the short-standing AF category (less than a year) and the long-standing AF category (more than a year). All patients had laboratory testing of 13C urea breath test, high-sensitive C-reactive protein (hs-CRP) and left atrial diameter (LAD). We analyzed the difference of these factors in all groups and explored the correlation between Hp infection and AF using logistic regression analysis.Results: Both AF groups had more hypertension, diabetes, and Hp infection than the control group. The Hp value and the hs-CRP level in patients with long-standing AF were higher than those in the short-standing AF and the control groups (for Hp value: P<0.001 for both and for hs-CRP level: P=0.003, 0.002, respectively). The LAD of patients in the long-standing AF group was significantly larger than those in the short-standing AF group and control group (P=0.001 and P<0.001, respectively). The values of Hp, hs-CRP, and LAD in the long-standing AF category were significantly higher than those in the short-standing AF category (all P<0.05). After controlling the potential confounders, Hp value ≥4&permil;, hs-CRP >5 mg/L, and LAD >36 mm were significantly related to long-standing AF.Conclusion: The values of Hp in patients with long-standing AF were significantly higher than those in short-standing AF and control groups. Hp δ value ≥4&permil; is an independent predictor for long-standing AF. Keywords: high sensitivity C-reactive protein, left atrial diameter,13C urea breath testA Letter to the Editor has been received and published for this article. Wang DZChen WYang SWang JLi QFu QLi SJChen BXDove Medical PressarticleHelicobacter pylorihigh sensitivity C-reactive proteinleft atrial diameteratrial fibrillation13C urea breath test.GeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 10, Pp 813-819 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Helicobacter pylori high sensitivity C-reactive protein left atrial diameter atrial fibrillation 13C urea breath test. Geriatrics RC952-954.6
spellingShingle	Helicobacter pylori high sensitivity C-reactive protein left atrial diameter atrial fibrillation 13C urea breath test. Geriatrics RC952-954.6 Wang DZ Chen W Yang S Wang J Li Q Fu Q Li SJ Chen BX Helicobacter pylori infection in Chinese patients with atrial fibrillation
description	De-Zhao Wang,1 Wei Chen,1 Song Yang,2 Jun Wang,3 Qun Li,1 Qiang Fu,2 Shi-Jing Li,3 Bu-Xing Chen1 1Department of Cardiology, Beijing Tiantan Hospital, Capital Medical University, 2Department of Ultrasonography, Beijing Tiantan Hospital, Capital Medical University, 3Department of Cardiology, Beijing Mentougou District Hospital, Beijing, People’s Republic of China Objective: To explore the relationship between Helicobacter pylori (Hp) infection and atrial fibrillation (AF) in Chinese patients.Methods: A total of 285 hospitalized patients with AF and 300 patients from Health Screening Center who matched age and sex with AF group were enrolled. AF patients were divided into two groups: the short-standing AF category (less than a year) and the long-standing AF category (more than a year). All patients had laboratory testing of 13C urea breath test, high-sensitive C-reactive protein (hs-CRP) and left atrial diameter (LAD). We analyzed the difference of these factors in all groups and explored the correlation between Hp infection and AF using logistic regression analysis.Results: Both AF groups had more hypertension, diabetes, and Hp infection than the control group. The Hp value and the hs-CRP level in patients with long-standing AF were higher than those in the short-standing AF and the control groups (for Hp value: P<0.001 for both and for hs-CRP level: P=0.003, 0.002, respectively). The LAD of patients in the long-standing AF group was significantly larger than those in the short-standing AF group and control group (P=0.001 and P<0.001, respectively). The values of Hp, hs-CRP, and LAD in the long-standing AF category were significantly higher than those in the short-standing AF category (all P<0.05). After controlling the potential confounders, Hp value ≥4&permil;, hs-CRP >5 mg/L, and LAD >36 mm were significantly related to long-standing AF.Conclusion: The values of Hp in patients with long-standing AF were significantly higher than those in short-standing AF and control groups. Hp δ value ≥4&permil; is an independent predictor for long-standing AF. Keywords: high sensitivity C-reactive protein, left atrial diameter,13C urea breath testA Letter to the Editor has been received and published for this article.
format	article
author	Wang DZ Chen W Yang S Wang J Li Q Fu Q Li SJ Chen BX
author_facet	Wang DZ Chen W Yang S Wang J Li Q Fu Q Li SJ Chen BX
author_sort	Wang DZ
title	Helicobacter pylori infection in Chinese patients with atrial fibrillation
title_short	Helicobacter pylori infection in Chinese patients with atrial fibrillation
title_full	Helicobacter pylori infection in Chinese patients with atrial fibrillation
title_fullStr	Helicobacter pylori infection in Chinese patients with atrial fibrillation
title_full_unstemmed	Helicobacter pylori infection in Chinese patients with atrial fibrillation
title_sort	helicobacter pylori infection in chinese patients with atrial fibrillation
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/d14613f66c6d4466b7131c0f2a567011
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_version_	1718403829762883584

Helicobacter pylori infection in Chinese patients with atrial fibrillation

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