Characterization of histone acylations links chromatin modifications with metabolism

A number of histone lysine modifications related to acetylation have been identified, but their functional significance is unclear. Here, the authors use in vitro and in vivo assays to characterize eight acyl histone post-translational modifications and link their abundance with metabolism.

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Autores principales:	Johayra Simithy, Simone Sidoli, Zuo-Fei Yuan, Mariel Coradin, Natarajan V. Bhanu, Dylan M. Marchione, Brianna J. Klein, Gleb A. Bazilevsky, Cheryl E. McCullough, Robert S. Magin, Tatiana G. Kutateladze, Nathaniel W. Snyder, Ronen Marmorstein, Benjamin A. Garcia
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d14a3bef3d85449ebebdccbdcf9b9c22
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spelling	oai:doaj.org-article:d14a3bef3d85449ebebdccbdcf9b9c222021-12-02T14:41:10ZCharacterization of histone acylations links chromatin modifications with metabolism10.1038/s41467-017-01384-92041-1723https://doaj.org/article/d14a3bef3d85449ebebdccbdcf9b9c222017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01384-9https://doaj.org/toc/2041-1723A number of histone lysine modifications related to acetylation have been identified, but their functional significance is unclear. Here, the authors use in vitro and in vivo assays to characterize eight acyl histone post-translational modifications and link their abundance with metabolism.Johayra SimithySimone SidoliZuo-Fei YuanMariel CoradinNatarajan V. BhanuDylan M. MarchioneBrianna J. KleinGleb A. BazilevskyCheryl E. McCulloughRobert S. MaginTatiana G. KutateladzeNathaniel W. SnyderRonen MarmorsteinBenjamin A. GarciaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Johayra Simithy Simone Sidoli Zuo-Fei Yuan Mariel Coradin Natarajan V. Bhanu Dylan M. Marchione Brianna J. Klein Gleb A. Bazilevsky Cheryl E. McCullough Robert S. Magin Tatiana G. Kutateladze Nathaniel W. Snyder Ronen Marmorstein Benjamin A. Garcia Characterization of histone acylations links chromatin modifications with metabolism
description	A number of histone lysine modifications related to acetylation have been identified, but their functional significance is unclear. Here, the authors use in vitro and in vivo assays to characterize eight acyl histone post-translational modifications and link their abundance with metabolism.
format	article
author	Johayra Simithy Simone Sidoli Zuo-Fei Yuan Mariel Coradin Natarajan V. Bhanu Dylan M. Marchione Brianna J. Klein Gleb A. Bazilevsky Cheryl E. McCullough Robert S. Magin Tatiana G. Kutateladze Nathaniel W. Snyder Ronen Marmorstein Benjamin A. Garcia
author_facet	Johayra Simithy Simone Sidoli Zuo-Fei Yuan Mariel Coradin Natarajan V. Bhanu Dylan M. Marchione Brianna J. Klein Gleb A. Bazilevsky Cheryl E. McCullough Robert S. Magin Tatiana G. Kutateladze Nathaniel W. Snyder Ronen Marmorstein Benjamin A. Garcia
author_sort	Johayra Simithy
title	Characterization of histone acylations links chromatin modifications with metabolism
title_short	Characterization of histone acylations links chromatin modifications with metabolism
title_full	Characterization of histone acylations links chromatin modifications with metabolism
title_fullStr	Characterization of histone acylations links chromatin modifications with metabolism
title_full_unstemmed	Characterization of histone acylations links chromatin modifications with metabolism
title_sort	characterization of histone acylations links chromatin modifications with metabolism
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/d14a3bef3d85449ebebdccbdcf9b9c22
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_version_	1718390022600654848

Characterization of histone acylations links chromatin modifications with metabolism

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