Maternal Plasma Lipid Concentration in Third Trimester of Women with Preeclampsia and Normotensive Pregnancy

Background: Preeclampsia is one of complications of pregnancy. It is responsible for morbidity for mother and fetus. Preeclampsia is a pregnancy multisystem disorder. Abnormal lipid profile has an effect on endothelial dysfunction. The association of serum lipid profile with preeclampsia is suggeste...

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Autores principales:	Ghada Mohammed, Waleed Ayad, Usama El-Gazzar, Samia Eid
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2020
Materias:	preeclampsia lipids apolipoprotein cholesterol triglycerides Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/d155038e304140c2b96a3418557755c6
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spelling	oai:doaj.org-article:d155038e304140c2b96a3418557755c62021-12-02T10:38:27ZMaternal Plasma Lipid Concentration in Third Trimester of Women with Preeclampsia and Normotensive Pregnancy2636-41742682-378010.21608/ijma.2020.23839.1101https://doaj.org/article/d155038e304140c2b96a3418557755c62020-04-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_78267_736e05ab68da0e25d013f8dbb542f6e9.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Preeclampsia is one of complications of pregnancy. It is responsible for morbidity for mother and fetus. Preeclampsia is a pregnancy multisystem disorder. Abnormal lipid profile has an effect on endothelial dysfunction. The association of serum lipid profile with preeclampsia is suggested to reflect new diagnostic tools. Pregnancy dyslipidemia is associated with an increased risk of preeclampsia. Compared to healthy pregnancy, women with preeclampsia have an abnormal lipid profile. Aim of the work: The aim of this work is comparison between normotensive women and preeclamptic women by serum lipid profile at third trimester. Patients and Methods: The present study conducted on 70 pregnant women in the Department of Obstetrics and Gynecology, at Al-Azhar University hospital [Damietta], which was conducted during 2019 [from April to December]. A study comprised 35 normotensive pregnant women as controls and 35 preeclampsia cases. The blood samples were analyzed for serum triglycerides [TGs], total cholesterol [TC], high-density lipoprotein-cholesterol [HDL-C], low-density Lipoprotein-Cholesterol [LDL-C], very low-density Lipoprotein-Cholesterol [VLDL-C], Apo lipoprotein- A1 [Apo-A1] and Apo lipoprotein- B[Apo-B]. Results: There was significant difference between group A and B as regard Apo B/ Apo A1, cholesterol, TGS, LDL and VLDL. They are higher in group B. Conclusion: In the third trimester of pregnancy, preeclamptic women have altered levels of serum lipid profile. The most significant test is Apo B/A1 ratio with accuracy [72.7%].Ghada MohammedWaleed AyadUsama El-GazzarSamia EidAl-Azhar University, Faculty of Medicine (Damietta)articlepreeclampsialipidsapolipoproteincholesteroltriglyceridesMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 2, Iss 2, Pp 405-411 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	preeclampsia lipids apolipoprotein cholesterol triglycerides Medicine (General) R5-920
spellingShingle	preeclampsia lipids apolipoprotein cholesterol triglycerides Medicine (General) R5-920 Ghada Mohammed Waleed Ayad Usama El-Gazzar Samia Eid Maternal Plasma Lipid Concentration in Third Trimester of Women with Preeclampsia and Normotensive Pregnancy
description	Background: Preeclampsia is one of complications of pregnancy. It is responsible for morbidity for mother and fetus. Preeclampsia is a pregnancy multisystem disorder. Abnormal lipid profile has an effect on endothelial dysfunction. The association of serum lipid profile with preeclampsia is suggested to reflect new diagnostic tools. Pregnancy dyslipidemia is associated with an increased risk of preeclampsia. Compared to healthy pregnancy, women with preeclampsia have an abnormal lipid profile. Aim of the work: The aim of this work is comparison between normotensive women and preeclamptic women by serum lipid profile at third trimester. Patients and Methods: The present study conducted on 70 pregnant women in the Department of Obstetrics and Gynecology, at Al-Azhar University hospital [Damietta], which was conducted during 2019 [from April to December]. A study comprised 35 normotensive pregnant women as controls and 35 preeclampsia cases. The blood samples were analyzed for serum triglycerides [TGs], total cholesterol [TC], high-density lipoprotein-cholesterol [HDL-C], low-density Lipoprotein-Cholesterol [LDL-C], very low-density Lipoprotein-Cholesterol [VLDL-C], Apo lipoprotein- A1 [Apo-A1] and Apo lipoprotein- B[Apo-B]. Results: There was significant difference between group A and B as regard Apo B/ Apo A1, cholesterol, TGS, LDL and VLDL. They are higher in group B. Conclusion: In the third trimester of pregnancy, preeclamptic women have altered levels of serum lipid profile. The most significant test is Apo B/A1 ratio with accuracy [72.7%].
format	article
author	Ghada Mohammed Waleed Ayad Usama El-Gazzar Samia Eid
author_facet	Ghada Mohammed Waleed Ayad Usama El-Gazzar Samia Eid
author_sort	Ghada Mohammed
title	Maternal Plasma Lipid Concentration in Third Trimester of Women with Preeclampsia and Normotensive Pregnancy
title_short	Maternal Plasma Lipid Concentration in Third Trimester of Women with Preeclampsia and Normotensive Pregnancy
title_full	Maternal Plasma Lipid Concentration in Third Trimester of Women with Preeclampsia and Normotensive Pregnancy
title_fullStr	Maternal Plasma Lipid Concentration in Third Trimester of Women with Preeclampsia and Normotensive Pregnancy
title_full_unstemmed	Maternal Plasma Lipid Concentration in Third Trimester of Women with Preeclampsia and Normotensive Pregnancy
title_sort	maternal plasma lipid concentration in third trimester of women with preeclampsia and normotensive pregnancy
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2020
url	https://doaj.org/article/d155038e304140c2b96a3418557755c6
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Maternal Plasma Lipid Concentration in Third Trimester of Women with Preeclampsia and Normotensive Pregnancy

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