Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use.
<h4>Aim</h4>To characterize the usage profile and the factors associated with the prolonged use of proton pump inhibitor drugs in a community pharmacy.<h4>Methodology</h4>This is a cross-sectional, prospective and observational study involving interviews with 410 patients who...
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| Autores principales: | , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Public Library of Science (PLoS)
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/d158349e62ad49f897372c89e2b8b239 |
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| Sumario: | <h4>Aim</h4>To characterize the usage profile and the factors associated with the prolonged use of proton pump inhibitor drugs in a community pharmacy.<h4>Methodology</h4>This is a cross-sectional, prospective and observational study involving interviews with 410 patients who acquired PPI for their own use from community pharmacies. To characterize the factors associated with the prolonged use of PPI, a multivariate logistic regression model was used.<h4>Results</h4>Pantoprazole (42.7%) and omeprazole (31%) were the most acquired PPIs, prescribed mainly by gastroenterologists (49.5%). They are used in the morning, especially for gastrointestinal symptoms, however, they had been consumed for more than 5 years in 30% of cases. The factors associated with prolonged use are old age (OR 1.03 CI95% 1.01-1.05), body mass index (OR 1.07 CI95% 1.01-1.12), use of non-steroidal anti-inflammatories (OR 3.18 CI95% 1.20-8.43) and selective serotonin reuptake inhibitors (OR 3.5 95% CI 1.39-8.88).<h4>Conclusion</h4>PPIs are adequate in terms of indication and form of use, however, prolonged use associated with old age, being overweight and use of anti-inflammatories and antidepressants is frequent. |
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