Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use.

<h4>Aim</h4>To characterize the usage profile and the factors associated with the prolonged use of proton pump inhibitor drugs in a community pharmacy.<h4>Methodology</h4>This is a cross-sectional, prospective and observational study involving interviews with 410 patients who...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Lorena Maria Lima de Araújo, Maria Vivyanne de Moura Lopes, Rafael Silva de Arruda, Rand Randall Martins, Antonio Gouveia Oliveira
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d158349e62ad49f897372c89e2b8b239
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d158349e62ad49f897372c89e2b8b239
record_format	dspace
spelling	oai:doaj.org-article:d158349e62ad49f897372c89e2b8b2392021-12-02T20:07:10ZProton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use.1932-620310.1371/journal.pone.0252785https://doaj.org/article/d158349e62ad49f897372c89e2b8b2392021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0252785https://doaj.org/toc/1932-6203<h4>Aim</h4>To characterize the usage profile and the factors associated with the prolonged use of proton pump inhibitor drugs in a community pharmacy.<h4>Methodology</h4>This is a cross-sectional, prospective and observational study involving interviews with 410 patients who acquired PPI for their own use from community pharmacies. To characterize the factors associated with the prolonged use of PPI, a multivariate logistic regression model was used.<h4>Results</h4>Pantoprazole (42.7%) and omeprazole (31%) were the most acquired PPIs, prescribed mainly by gastroenterologists (49.5%). They are used in the morning, especially for gastrointestinal symptoms, however, they had been consumed for more than 5 years in 30% of cases. The factors associated with prolonged use are old age (OR 1.03 CI95% 1.01-1.05), body mass index (OR 1.07 CI95% 1.01-1.12), use of non-steroidal anti-inflammatories (OR 3.18 CI95% 1.20-8.43) and selective serotonin reuptake inhibitors (OR 3.5 95% CI 1.39-8.88).<h4>Conclusion</h4>PPIs are adequate in terms of indication and form of use, however, prolonged use associated with old age, being overweight and use of anti-inflammatories and antidepressants is frequent.Lorena Maria Lima de AraújoMaria Vivyanne de Moura LopesRafael Silva de ArrudaRand Randall MartinsAntonio Gouveia OliveiraPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0252785 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Lorena Maria Lima de Araújo Maria Vivyanne de Moura Lopes Rafael Silva de Arruda Rand Randall Martins Antonio Gouveia Oliveira Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use.
description	<h4>Aim</h4>To characterize the usage profile and the factors associated with the prolonged use of proton pump inhibitor drugs in a community pharmacy.<h4>Methodology</h4>This is a cross-sectional, prospective and observational study involving interviews with 410 patients who acquired PPI for their own use from community pharmacies. To characterize the factors associated with the prolonged use of PPI, a multivariate logistic regression model was used.<h4>Results</h4>Pantoprazole (42.7%) and omeprazole (31%) were the most acquired PPIs, prescribed mainly by gastroenterologists (49.5%). They are used in the morning, especially for gastrointestinal symptoms, however, they had been consumed for more than 5 years in 30% of cases. The factors associated with prolonged use are old age (OR 1.03 CI95% 1.01-1.05), body mass index (OR 1.07 CI95% 1.01-1.12), use of non-steroidal anti-inflammatories (OR 3.18 CI95% 1.20-8.43) and selective serotonin reuptake inhibitors (OR 3.5 95% CI 1.39-8.88).<h4>Conclusion</h4>PPIs are adequate in terms of indication and form of use, however, prolonged use associated with old age, being overweight and use of anti-inflammatories and antidepressants is frequent.
format	article
author	Lorena Maria Lima de Araújo Maria Vivyanne de Moura Lopes Rafael Silva de Arruda Rand Randall Martins Antonio Gouveia Oliveira
author_facet	Lorena Maria Lima de Araújo Maria Vivyanne de Moura Lopes Rafael Silva de Arruda Rand Randall Martins Antonio Gouveia Oliveira
author_sort	Lorena Maria Lima de Araújo
title	Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use.
title_short	Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use.
title_full	Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use.
title_fullStr	Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use.
title_full_unstemmed	Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use.
title_sort	proton pump inhibitor and community pharmacies: usage profile and factors associated with long-term use.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/d158349e62ad49f897372c89e2b8b239
work_keys_str_mv	AT lorenamarialimadearaujo protonpumpinhibitorandcommunitypharmaciesusageprofileandfactorsassociatedwithlongtermuse AT mariavivyannedemouralopes protonpumpinhibitorandcommunitypharmaciesusageprofileandfactorsassociatedwithlongtermuse AT rafaelsilvadearruda protonpumpinhibitorandcommunitypharmaciesusageprofileandfactorsassociatedwithlongtermuse AT randrandallmartins protonpumpinhibitorandcommunitypharmaciesusageprofileandfactorsassociatedwithlongtermuse AT antoniogouveiaoliveira protonpumpinhibitorandcommunitypharmaciesusageprofileandfactorsassociatedwithlongtermuse
_version_	1718375330469642240

Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use.

Ejemplares similares