Reducing MSH4 copy number prevents meiotic crossovers between non-homologous chromosomes in Brassica napus

Non-homologous crossovers impair correct chromosome segregation in allopolyploids. Here the authors show that most non-homologous crossovers in Brassica napus arise from MSH4-dependent recombination and provide evidence that post-polyploidization reduction of MSH4 duplicate stabilizes meiosis.

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Autores principales:	Adrián Gonzalo, Marie-Odile Lucas, Catherine Charpentier, Greta Sandmann, Andrew Lloyd, Eric Jenczewski
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d15b2afdd223409c9dabd7168d99dfbb
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spelling	oai:doaj.org-article:d15b2afdd223409c9dabd7168d99dfbb2021-12-02T17:31:53ZReducing MSH4 copy number prevents meiotic crossovers between non-homologous chromosomes in Brassica napus10.1038/s41467-019-10010-92041-1723https://doaj.org/article/d15b2afdd223409c9dabd7168d99dfbb2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10010-9https://doaj.org/toc/2041-1723Non-homologous crossovers impair correct chromosome segregation in allopolyploids. Here the authors show that most non-homologous crossovers in Brassica napus arise from MSH4-dependent recombination and provide evidence that post-polyploidization reduction of MSH4 duplicate stabilizes meiosis.Adrián GonzaloMarie-Odile LucasCatherine CharpentierGreta SandmannAndrew LloydEric JenczewskiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Adrián Gonzalo Marie-Odile Lucas Catherine Charpentier Greta Sandmann Andrew Lloyd Eric Jenczewski Reducing MSH4 copy number prevents meiotic crossovers between non-homologous chromosomes in Brassica napus
description	Non-homologous crossovers impair correct chromosome segregation in allopolyploids. Here the authors show that most non-homologous crossovers in Brassica napus arise from MSH4-dependent recombination and provide evidence that post-polyploidization reduction of MSH4 duplicate stabilizes meiosis.
format	article
author	Adrián Gonzalo Marie-Odile Lucas Catherine Charpentier Greta Sandmann Andrew Lloyd Eric Jenczewski
author_facet	Adrián Gonzalo Marie-Odile Lucas Catherine Charpentier Greta Sandmann Andrew Lloyd Eric Jenczewski
author_sort	Adrián Gonzalo
title	Reducing MSH4 copy number prevents meiotic crossovers between non-homologous chromosomes in Brassica napus
title_short	Reducing MSH4 copy number prevents meiotic crossovers between non-homologous chromosomes in Brassica napus
title_full	Reducing MSH4 copy number prevents meiotic crossovers between non-homologous chromosomes in Brassica napus
title_fullStr	Reducing MSH4 copy number prevents meiotic crossovers between non-homologous chromosomes in Brassica napus
title_full_unstemmed	Reducing MSH4 copy number prevents meiotic crossovers between non-homologous chromosomes in Brassica napus
title_sort	reducing msh4 copy number prevents meiotic crossovers between non-homologous chromosomes in brassica napus
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d15b2afdd223409c9dabd7168d99dfbb
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Reducing MSH4 copy number prevents meiotic crossovers between non-homologous chromosomes in Brassica napus

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