Reducing MSH4 copy number prevents meiotic crossovers between non-homologous chromosomes in Brassica napus

Reducing MSH4 copy number prevents meiotic crossovers between non-homologous chromosomes in Brassica napus

Non-homologous crossovers impair correct chromosome segregation in allopolyploids. Here the authors show that most non-homologous crossovers in Brassica napus arise from MSH4-dependent recombination and provide evidence that post-polyploidization reduction of MSH4 duplicate stabilizes meiosis.

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Autores principales: Adrián Gonzalo, Marie-Odile Lucas, Catherine Charpentier, Greta Sandmann, Andrew Lloyd, Eric Jenczewski
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/d15b2afdd223409c9dabd7168d99dfbb
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