Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse

Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse

How Nodal and Bmp pathways interact during primordial germ cell (PGC) formation remains unclear. Here, the authors show Nodal signalling via Eomes in the epiblast, together with Smad2 in the visceral endoderm, regulates formation of the mouse PGC lineage, while Smad1 specifies PGCs and Smad4 control...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Anna D. Senft, Elizabeth K. Bikoff, Elizabeth J. Robertson, Ita Costello
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/d165dcef375f4774be02535361889157
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares