Epithelial-mesenchymal-transition-like and TGFβ pathways associated with autochthonous inflammatory melanoma development in mice.

Epithelial-mesenchymal-transition-like and TGFβ pathways associated with autochthonous inflammatory melanoma development in mice.

We compared gene expression signatures of aggressive amelanotic (Amela) melanomas with those of slowly growing pigmented melanomas (Mela), identifying pathways potentially responsible for the aggressive Amela phenotype. Both tumors develop in mice upon conditional deletion in melanocytes of Ink4a/Ar...

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Autores principales: Maria Wehbe, Saïdi M Soudja, Amandine Mas, Lionel Chasson, Rodolphe Guinamard, Céline Powis de Tenbossche, Grégory Verdeil, Benoît Van den Eynde, Anne-Marie Schmitt-Verhulst
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/d167be50080642eabd99670a5d3de325
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